ECTRIMS eLearning

Cognitive rehabilitation and neuroimaging
ECTRIMS Learn. DeLuca J. 10/10/18; 231838; 95
John DeLuca
John DeLuca
Contributions
Abstract

Abstract: 95

Type: Scientific Session

Abstract Category: N/A

It is now well established that up to 70% of persons with multiple sclerosis (MS) suffer from cognitive impairment. Given the frequency and degree of cognitive involvement in persons with MS, and how it affects so many aspects of a person's life (e.g., vocational, familial, social, emotional, cultural) the need for cognitive rehabilitation therapies and programs is clear. This presentation will describe how neuroimaging is used in cognitive rehabilitation in persons with MS.
A recent review of functional and structural brain plasticity use in cognitive rehabilitation studies in persons with MS showed that cognitive rehabilitation treatment resulted in increased activation in various brain regions (depending on the nature of the intervention) compared to placebo (Prosperini et al., 2015). Further, the training-induced brain plasticity was correlated with cognitive improvements in the treatment group. This presentation will provide a critical review of these and more recent studies and discuss a framework for future studies.
Disclosure: Grants from Biogen IDEC; EMD Serono
Consultation from Biogen IDEC, Celgene, Sanofi-Genzyme
Speaking fees from EMD Serono, Sanofi-Genzyme

Abstract: 95

Type: Scientific Session

Abstract Category: N/A

It is now well established that up to 70% of persons with multiple sclerosis (MS) suffer from cognitive impairment. Given the frequency and degree of cognitive involvement in persons with MS, and how it affects so many aspects of a person's life (e.g., vocational, familial, social, emotional, cultural) the need for cognitive rehabilitation therapies and programs is clear. This presentation will describe how neuroimaging is used in cognitive rehabilitation in persons with MS.
A recent review of functional and structural brain plasticity use in cognitive rehabilitation studies in persons with MS showed that cognitive rehabilitation treatment resulted in increased activation in various brain regions (depending on the nature of the intervention) compared to placebo (Prosperini et al., 2015). Further, the training-induced brain plasticity was correlated with cognitive improvements in the treatment group. This presentation will provide a critical review of these and more recent studies and discuss a framework for future studies.
Disclosure: Grants from Biogen IDEC; EMD Serono
Consultation from Biogen IDEC, Celgene, Sanofi-Genzyme
Speaking fees from EMD Serono, Sanofi-Genzyme

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