Contributions
Abstract: EP1727
Type: Poster Sessions
Abstract Category: Therapy - Others
Introduction: Pregnancy and lactation are important issues for women with multiple sclerosis(MS). The purpose of this study was to investigate the effect of pregnancy and exclusive breastfeeding on the rate of relapses and degree of disability in two years after pregnancy in patients with relapsing remitting multiple sclerosis(RRMS).
Materials and methods: 30 RRMS pregnant women who had exclusive breastfeeding for 4 months were compared with 67 non-pregnant women with RRMS as controls from 2012 to 2017. Each patient was examined every three months for 33 months.
Findings: In the first group, patients were examined at the beginning of pregnancy, and then every three months to 24 months after delivery. Expaned disability status scale (EDSS) in the third trimester of pregnancy, third to ninth month after delivery, the last 6 months of study and collectively at the end of the study were significantly lower than the control group (p < 05). Also, EDSS in the second and third trimesters of pregnancy was significantly decreased compared to the initial EDSS (p < .05). The mean number of relapses in the second and third trimesters of pregnancy, the third to sixth month after delivery, and the total number of relapses were significantly lower than the control group.
Conclusion: Exclusive breastfeeding after pregnancy can have a positive effect on reducing relapse rate and disability, and this effect will continue until the 24th month after childbirth.
Disclosure: -all authors: nothing to disclose
-no conflict of interest and source of funding for all authors
Abstract: EP1727
Type: Poster Sessions
Abstract Category: Therapy - Others
Introduction: Pregnancy and lactation are important issues for women with multiple sclerosis(MS). The purpose of this study was to investigate the effect of pregnancy and exclusive breastfeeding on the rate of relapses and degree of disability in two years after pregnancy in patients with relapsing remitting multiple sclerosis(RRMS).
Materials and methods: 30 RRMS pregnant women who had exclusive breastfeeding for 4 months were compared with 67 non-pregnant women with RRMS as controls from 2012 to 2017. Each patient was examined every three months for 33 months.
Findings: In the first group, patients were examined at the beginning of pregnancy, and then every three months to 24 months after delivery. Expaned disability status scale (EDSS) in the third trimester of pregnancy, third to ninth month after delivery, the last 6 months of study and collectively at the end of the study were significantly lower than the control group (p < 05). Also, EDSS in the second and third trimesters of pregnancy was significantly decreased compared to the initial EDSS (p < .05). The mean number of relapses in the second and third trimesters of pregnancy, the third to sixth month after delivery, and the total number of relapses were significantly lower than the control group.
Conclusion: Exclusive breastfeeding after pregnancy can have a positive effect on reducing relapse rate and disability, and this effect will continue until the 24th month after childbirth.
Disclosure: -all authors: nothing to disclose
-no conflict of interest and source of funding for all authors