Contributions
Abstract: EP1491
Type: Poster Sessions
Abstract Category: Pathology and pathogenesis of MS - Environmental factors
Introduction: It is known that environmental and genetic factors are implicated in the pathogenesis of multiple sclerosis (MS). Currently there are no studies evaluating the correlation between dietary habits during adolescence and MS in areas near the equator.
Objective: To determine whether there is an association between MS and dietary habits during adolescence.
Aims: Uncrease knowledge about risk factors for multiple sclerosis in our region.
Methods: With a cross-sectional study, we applied a questionnaire including dietary habits during adolescence to 87 patients with MS and 87 healthy subjects. Information regarding sunlight exposure, physical activity, personal and family medical history, and hormonal factors was also collected. A blood sample was gathered to measure vitamin D and Epstein-Barr virus antibodies. Bivariate and multivariate analysis were performed with MS status as the outcome.
Results: 174 participants were analysed, patients (n=87) had a mean age at enrolment of 40.9 years and 65.52% of them were women. 83.9% had relapsing-remitting MS, 6.89% secondary-progressive MS and 4.59% primary-progressive MS. Multivariate analysis showed significant association between fast food and sugary drinks consumption during adolescence and MS (OR 6.14, CI95% 1.68-22.34, p=0.006; OR 3.72, CI95% 1.25-11.09, p=0.018). Dairy products, gluten, meat, alcohol, coffee, seafood, fruits, vegetables, eggs and grains consumption did not have a significant association. As sugary drinks and fast food could be confounding factors for each other, an additional analysis controlling for both was done which showed that only fast food consumption during adolescence was significantly associated with MS (OR 4.94, CI95% 1.29-18.93, p=0.02).
Conclusions: Fast food consumption during adolescence significantly increases the risk of later MS development. Additional studies should be done to evaluate this association in other regions in Latin America and near the equator.
Disclosure: Jaime Toro is Associate Editor for Watch Neurology and Board Member of Multiple Sclerosis and Related Disorders Journal.
Camilo Díaz: nothing to disclose.
Saúl Reyes: nothing to disclose.
María Reyes-Mantilla: nothing to disclose.
David Cuellar-Giraldo: nothing to disclose.
Alejandra Duque: nothing to disclose.
Fabian Cortes: nothing to disclose.
Camilo Torres: nothing to disclose.
Jorge Rios: nothing to disclose.
Jorge Patiño: nothing to disclose.
Abstract: EP1491
Type: Poster Sessions
Abstract Category: Pathology and pathogenesis of MS - Environmental factors
Introduction: It is known that environmental and genetic factors are implicated in the pathogenesis of multiple sclerosis (MS). Currently there are no studies evaluating the correlation between dietary habits during adolescence and MS in areas near the equator.
Objective: To determine whether there is an association between MS and dietary habits during adolescence.
Aims: Uncrease knowledge about risk factors for multiple sclerosis in our region.
Methods: With a cross-sectional study, we applied a questionnaire including dietary habits during adolescence to 87 patients with MS and 87 healthy subjects. Information regarding sunlight exposure, physical activity, personal and family medical history, and hormonal factors was also collected. A blood sample was gathered to measure vitamin D and Epstein-Barr virus antibodies. Bivariate and multivariate analysis were performed with MS status as the outcome.
Results: 174 participants were analysed, patients (n=87) had a mean age at enrolment of 40.9 years and 65.52% of them were women. 83.9% had relapsing-remitting MS, 6.89% secondary-progressive MS and 4.59% primary-progressive MS. Multivariate analysis showed significant association between fast food and sugary drinks consumption during adolescence and MS (OR 6.14, CI95% 1.68-22.34, p=0.006; OR 3.72, CI95% 1.25-11.09, p=0.018). Dairy products, gluten, meat, alcohol, coffee, seafood, fruits, vegetables, eggs and grains consumption did not have a significant association. As sugary drinks and fast food could be confounding factors for each other, an additional analysis controlling for both was done which showed that only fast food consumption during adolescence was significantly associated with MS (OR 4.94, CI95% 1.29-18.93, p=0.02).
Conclusions: Fast food consumption during adolescence significantly increases the risk of later MS development. Additional studies should be done to evaluate this association in other regions in Latin America and near the equator.
Disclosure: Jaime Toro is Associate Editor for Watch Neurology and Board Member of Multiple Sclerosis and Related Disorders Journal.
Camilo Díaz: nothing to disclose.
Saúl Reyes: nothing to disclose.
María Reyes-Mantilla: nothing to disclose.
David Cuellar-Giraldo: nothing to disclose.
Alejandra Duque: nothing to disclose.
Fabian Cortes: nothing to disclose.
Camilo Torres: nothing to disclose.
Jorge Rios: nothing to disclose.
Jorge Patiño: nothing to disclose.