Contributions
Abstract: EP1488
Type: Poster Sessions
Abstract Category: Pathology and pathogenesis of MS - Environmental factors
Introduction: Previous studies on caffeine and risk of MS yielded different results; one study suggests a positive effect on disease progression.
Aims: We aimed to investigate if coffee consumption is associated with MS disability.
Methods: Questionnaires were applied to 126 MS patients that attended Neuroimmunology consultation between January-November/2017. MS severity was evaluated by EDSS, 9-HPT, T25-FW and SDMT. High coffee intake was considered ≥4 cups/day; lifetime consumption was calculated multiplying espressos per day by years of consumption. Fisher exact test (categorical variables), Mann-Whitney test (categorical and continuous variables) and Pearson correlations (continuous variables) were used.
Results: Our cohort had an average age of 45.3 years and 76 (60.3%) were women. Mean age of MS onset was 29.7 years and mean duration of disease 15.6 years. Seventy-nine percent had relapsing-remitting MS; 50% had EDSS 0-3.5, 35.7% EDSS=3.5-6.0, and 14.3% EDSS≥6.0. Regular coffee intake was observed for 78.6%. High coffee intake was present in 17.2%.
Men had more high coffee intake (29% vs 10.3%, p=0.03) but total coffee consumption was not different between genders (p=0.48). High coffee intake and total coffee consumption was associated with higher smoking habits (3.85 vs 0 pack-years,p=0.01;r=0.29,p< 0.001).
No significant association was found between EDSS and high coffee intake or total coffee consumption (3 vs 3.5,p=0.79;r=0.06,p=0.48). Also, we did not find any differences regarding coffee intake and performance in 9-HPT, T25-FW and SDMT.
Conclusions: In our cohort, coffee consumption does not seem to have a role in progression of disability. Further studies, namely prospective, are required to access this association.
Disclosure: All authors have nothing to disclose.
Abstract: EP1488
Type: Poster Sessions
Abstract Category: Pathology and pathogenesis of MS - Environmental factors
Introduction: Previous studies on caffeine and risk of MS yielded different results; one study suggests a positive effect on disease progression.
Aims: We aimed to investigate if coffee consumption is associated with MS disability.
Methods: Questionnaires were applied to 126 MS patients that attended Neuroimmunology consultation between January-November/2017. MS severity was evaluated by EDSS, 9-HPT, T25-FW and SDMT. High coffee intake was considered ≥4 cups/day; lifetime consumption was calculated multiplying espressos per day by years of consumption. Fisher exact test (categorical variables), Mann-Whitney test (categorical and continuous variables) and Pearson correlations (continuous variables) were used.
Results: Our cohort had an average age of 45.3 years and 76 (60.3%) were women. Mean age of MS onset was 29.7 years and mean duration of disease 15.6 years. Seventy-nine percent had relapsing-remitting MS; 50% had EDSS 0-3.5, 35.7% EDSS=3.5-6.0, and 14.3% EDSS≥6.0. Regular coffee intake was observed for 78.6%. High coffee intake was present in 17.2%.
Men had more high coffee intake (29% vs 10.3%, p=0.03) but total coffee consumption was not different between genders (p=0.48). High coffee intake and total coffee consumption was associated with higher smoking habits (3.85 vs 0 pack-years,p=0.01;r=0.29,p< 0.001).
No significant association was found between EDSS and high coffee intake or total coffee consumption (3 vs 3.5,p=0.79;r=0.06,p=0.48). Also, we did not find any differences regarding coffee intake and performance in 9-HPT, T25-FW and SDMT.
Conclusions: In our cohort, coffee consumption does not seem to have a role in progression of disability. Further studies, namely prospective, are required to access this association.
Disclosure: All authors have nothing to disclose.