ECTRIMS eLearning

Relationship between upper and lower limb impairments objectively assessed in people with multiple sclerosis
Author(s): ,
G. Coghe
Affiliations:
Centro SM - Osp. Binaghi | Department of Medical Science and Public Health | University of Cagliari
,
F. Corona
Affiliations:
Dipartimento di Ingegneria Meccanica Chimica e dei Materiali, University of Cagliari, Cagliari, Italy
,
M. Porta
Affiliations:
Dipartimento di Ingegneria Meccanica Chimica e dei Materiali, University of Cagliari, Cagliari, Italy
,
G. Pilloni
Affiliations:
Dipartimento di Ingegneria Meccanica Chimica e dei Materiali, University of Cagliari, Cagliari, Italy
,
M. Pau
Affiliations:
Dipartimento di Ingegneria Meccanica Chimica e dei Materiali, University of Cagliari, Cagliari, Italy
E. Cocco
Affiliations:
Dipartimento di Ingegneria Meccanica Chimica e dei Materiali, University of Cagliari, Cagliari, Italy
ECTRIMS Learn. Coghe G. 10/10/18; 229265; EP1427
Giancarlo Coghe
Giancarlo Coghe
Contributions
Abstract

Abstract: EP1427

Type: Poster Sessions

Abstract Category: Clinical aspects of MS - Clinical assessment tools

Aims: To investigate the relationships between UL and LL impairments in pwMS while performing motor tasks relevant for their quality of life, such as walking and “hand-to-mouth” (HTM) movement.
Methods: Twenty-four pwMS (EDSS: 3.8±2.3, range 1-6) underwent a 3D kinematic analysis during gait and HTM movements. The following parameters were computed: for HTM, overall movement duration, velocity, smoothness and adjusting sway (AS, length of the trajectory during mouth localization); for gait, speed, stride time and length and cadence. Correlations between UL and LL parameters and between EDSS and UL/LL parameters were assessed using Spearman´s rank coefficient.
Results: Moderate correlations were found between total HTM duration and stride time (rho=0.56, p< 0.01), and between HTM velocity and gait speed (rho=0.35, p< 0.05). The precision of the HTM movement, expressed by AS, was also found moderately correlated with gait speed (rho=-0.36, p< 0.05) and stride length (rho=-0.34, p< 0.05). The index associated with movement smoothness was found negatively correlated with gait speed (rho=-0.31, p< 0.05). Lastly, EDSS was found weakly correlated with total HTM duration (rho=0.35, p< 0.05) and strongly correlated with gait speed (rho=-0.85, p< 0.01).
Conclusions: UL and LL motor abilities in pwMS appear weakly-moderately correlated, although both worsen as disability increases. This suggests UL and LL impairments should be separately assessed using specific tests to have a whole view of the motor functions in MS. However further studies on a larger set of UL movements are needed to verify if such lack of relationship is confirmed.
Disclosure: The authors have nothing to disclose

Abstract: EP1427

Type: Poster Sessions

Abstract Category: Clinical aspects of MS - Clinical assessment tools

Aims: To investigate the relationships between UL and LL impairments in pwMS while performing motor tasks relevant for their quality of life, such as walking and “hand-to-mouth” (HTM) movement.
Methods: Twenty-four pwMS (EDSS: 3.8±2.3, range 1-6) underwent a 3D kinematic analysis during gait and HTM movements. The following parameters were computed: for HTM, overall movement duration, velocity, smoothness and adjusting sway (AS, length of the trajectory during mouth localization); for gait, speed, stride time and length and cadence. Correlations between UL and LL parameters and between EDSS and UL/LL parameters were assessed using Spearman´s rank coefficient.
Results: Moderate correlations were found between total HTM duration and stride time (rho=0.56, p< 0.01), and between HTM velocity and gait speed (rho=0.35, p< 0.05). The precision of the HTM movement, expressed by AS, was also found moderately correlated with gait speed (rho=-0.36, p< 0.05) and stride length (rho=-0.34, p< 0.05). The index associated with movement smoothness was found negatively correlated with gait speed (rho=-0.31, p< 0.05). Lastly, EDSS was found weakly correlated with total HTM duration (rho=0.35, p< 0.05) and strongly correlated with gait speed (rho=-0.85, p< 0.01).
Conclusions: UL and LL motor abilities in pwMS appear weakly-moderately correlated, although both worsen as disability increases. This suggests UL and LL impairments should be separately assessed using specific tests to have a whole view of the motor functions in MS. However further studies on a larger set of UL movements are needed to verify if such lack of relationship is confirmed.
Disclosure: The authors have nothing to disclose

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