Contributions
Abstract: EP1387
Type: Poster Sessions
Abstract Category: Clinical aspects of MS - MS symptoms
Introduction: Benign multiple sclerosis (B-MS) patients display preserved somatic neurological functions but nevertheless other nervous system faculties such as cognitive functions may be impaired.
Objective: Our aim was to explore the status of sleep functions in B-MS.
Methods: Age, gender and disease duration-matched B-MS (EDSS < 3.0 more than 10 years after MS onset) (n=12) and non-benign MS (NB-MS, n=18) patients were recruited for evaluation of sleep functions. All patients were in the remission stage, using immunomodulating medications. None of the patients had received steroid treatment in the last 3 months. Detailed sleep history was obtained, Epworth Sleepiness Score (ESS) and Pittsburgh Sleep Quality Index (PSQI) were employed. Full night polysomnography (PSG) recordings were performed by two blinded sleep specialists. Sleep disorder prevalences were compared with chi-square test and PSG parameters were compared with Mann-Whitney U.
Results: Twenty (67%) MS patients (8 B-MS and 12 NB-MS; p>0.999) displayed multiple sleep disorders including obstructive sleep apnea syndrome (12), periodic limb movement disorder (8), restless legs syndrome (4), REM sleep behavior disorder (1) and insomnia (1). There were no significant differences among B-MS and NB-MS patients by means of ESS and PSQI scores, sleep efficiency index, sleep continuity index, sleep latency, rapid eye movement latency, duration of each sleep stage, oxygen saturation and periodic leg movements in sleep (PLMS) index.
Conclusions: Sleep disorder prevalence of B-MS patients is comparable to that of NB-MS patients, indicating involvement of sleep related brain regions in this MS subtype despite apparent preservation of motor, sensory and visual domains.
Disclosure: Recai Türkoğlu: nothing to disclose
Erdem Tüzün: nothing to disclose
Gülçin Benbir: nothing to disclose
Selen Özyurt: nothing to disclose
Mustafa İskender: nothing to disclose
Derya Karadeniz: nothing to disclose
Abstract: EP1387
Type: Poster Sessions
Abstract Category: Clinical aspects of MS - MS symptoms
Introduction: Benign multiple sclerosis (B-MS) patients display preserved somatic neurological functions but nevertheless other nervous system faculties such as cognitive functions may be impaired.
Objective: Our aim was to explore the status of sleep functions in B-MS.
Methods: Age, gender and disease duration-matched B-MS (EDSS < 3.0 more than 10 years after MS onset) (n=12) and non-benign MS (NB-MS, n=18) patients were recruited for evaluation of sleep functions. All patients were in the remission stage, using immunomodulating medications. None of the patients had received steroid treatment in the last 3 months. Detailed sleep history was obtained, Epworth Sleepiness Score (ESS) and Pittsburgh Sleep Quality Index (PSQI) were employed. Full night polysomnography (PSG) recordings were performed by two blinded sleep specialists. Sleep disorder prevalences were compared with chi-square test and PSG parameters were compared with Mann-Whitney U.
Results: Twenty (67%) MS patients (8 B-MS and 12 NB-MS; p>0.999) displayed multiple sleep disorders including obstructive sleep apnea syndrome (12), periodic limb movement disorder (8), restless legs syndrome (4), REM sleep behavior disorder (1) and insomnia (1). There were no significant differences among B-MS and NB-MS patients by means of ESS and PSQI scores, sleep efficiency index, sleep continuity index, sleep latency, rapid eye movement latency, duration of each sleep stage, oxygen saturation and periodic leg movements in sleep (PLMS) index.
Conclusions: Sleep disorder prevalence of B-MS patients is comparable to that of NB-MS patients, indicating involvement of sleep related brain regions in this MS subtype despite apparent preservation of motor, sensory and visual domains.
Disclosure: Recai Türkoğlu: nothing to disclose
Erdem Tüzün: nothing to disclose
Gülçin Benbir: nothing to disclose
Selen Özyurt: nothing to disclose
Mustafa İskender: nothing to disclose
Derya Karadeniz: nothing to disclose