ECTRIMS eLearning

Factors related to restless leg syndrome in multiple sclerosis
Author(s): ,
A.T. Ozdogar
Affiliations:
Dokuz Eylul University, Izmir
,
Z. Abasiyanik
Affiliations:
Dokuz Eylul University
,
T. Kahraman
Affiliations:
Izmir Katip Celebi University, IZMIR, Turkey
,
O. Ertekin
Affiliations:
Dokuz Eylul University
,
S. Ozakbas
Affiliations:
Dokuz Eylul University
Multiple Sclerosis Research Group
Multiple Sclerosis Research Group
Affiliations:
ECTRIMS Learn. Özdoğar A. 10/10/18; 229223; EP1384
Asiye Tuba Özdoğar
Asiye Tuba Özdoğar
Contributions
Abstract

Abstract: EP1384

Type: Poster Sessions

Abstract Category: Clinical aspects of MS - MS symptoms

Restless Leg Syndrome (RLS) has been reported in people with multiple sclerosis (MS, pwMS) ranging from 12.12% to 57.5%. This ratio is 4 times higher than general populations. Dopaminergic dysfunction and spinal cord lesions may play a role in the presence of more RLS in pwMS. Patients with central dopaminergic dysfunction have difficulties in performing or initiating alternative movements.
The aim of this study is to evaluate the gait function, balance and MRI findings in MS with RLS.
In total, 299 pwMS were enrolled in this study. The diagnosis of RLS used the criteria defined by the International Restless Legs Syndrome Study Group. Walking function was assessed with 12-Item Multiple Sclerosis Walking Scale (MSWS-12), Timed 25-Foot Walk (T25FW), Timed Up and Go Test (TUG) and the 6 Minute Walk Test (6MWT), balance was assessed with Activity-Specific Balance Confidence Scale (ABC) and One Leg Stand Test (OLST). The presence of spinal cord lesion was determined by the neurologist.
The RLS was detected in 88 (29.43%) of the 299 pwMS who participated in the study. The MSWS-12 and ABC score was a significantly higher in participants with RLS than without RLS (p < 0.05). On the other hand, there was no significant difference between the participants with RLS and without RLS in terms of performance-based outcome measures such as T25FW, TUG, 6MWT and OLST and presence of spinal cord lesion (p> 0.05).
This study has suggested that the pwMS with RLS have less perceived walking and balance ability compared to without RLS. However, the performance of a walking function, balance, and presence of spinal cord lesion was similar compared to pwMS without RLS. Although this lack of perceived does not affect the performance, early assessment and rehabilitation program for the lower extremities are important to prevent possible functional deficits in pwMS with RLS.
Disclosure: Asiye Tuba Ozdogar: nothing to disclose
Zuhal Abasıyanık: nothing to disclose
Turhan Kahraman: nothing to disclose
Ozge Ertekin: nothing to disclose
Serkan Ozakbas: nothing to disclose

Abstract: EP1384

Type: Poster Sessions

Abstract Category: Clinical aspects of MS - MS symptoms

Restless Leg Syndrome (RLS) has been reported in people with multiple sclerosis (MS, pwMS) ranging from 12.12% to 57.5%. This ratio is 4 times higher than general populations. Dopaminergic dysfunction and spinal cord lesions may play a role in the presence of more RLS in pwMS. Patients with central dopaminergic dysfunction have difficulties in performing or initiating alternative movements.
The aim of this study is to evaluate the gait function, balance and MRI findings in MS with RLS.
In total, 299 pwMS were enrolled in this study. The diagnosis of RLS used the criteria defined by the International Restless Legs Syndrome Study Group. Walking function was assessed with 12-Item Multiple Sclerosis Walking Scale (MSWS-12), Timed 25-Foot Walk (T25FW), Timed Up and Go Test (TUG) and the 6 Minute Walk Test (6MWT), balance was assessed with Activity-Specific Balance Confidence Scale (ABC) and One Leg Stand Test (OLST). The presence of spinal cord lesion was determined by the neurologist.
The RLS was detected in 88 (29.43%) of the 299 pwMS who participated in the study. The MSWS-12 and ABC score was a significantly higher in participants with RLS than without RLS (p < 0.05). On the other hand, there was no significant difference between the participants with RLS and without RLS in terms of performance-based outcome measures such as T25FW, TUG, 6MWT and OLST and presence of spinal cord lesion (p> 0.05).
This study has suggested that the pwMS with RLS have less perceived walking and balance ability compared to without RLS. However, the performance of a walking function, balance, and presence of spinal cord lesion was similar compared to pwMS without RLS. Although this lack of perceived does not affect the performance, early assessment and rehabilitation program for the lower extremities are important to prevent possible functional deficits in pwMS with RLS.
Disclosure: Asiye Tuba Ozdogar: nothing to disclose
Zuhal Abasıyanık: nothing to disclose
Turhan Kahraman: nothing to disclose
Ozge Ertekin: nothing to disclose
Serkan Ozakbas: nothing to disclose

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