Contributions
Abstract: EP1348
Type: Poster Sessions
Abstract Category: Clinical aspects of MS - Epidemiology
Introduction:The epidemiology of Multiple Sclerosis (MS) in Ardabil, north-western region of Iran is unknown.
Aims: We aimed to design a study to evaluate the epidemiology of MS in Ardabil.
Methods: A retrospective population-based cross-sectional study was conducted from 2007 to 2017 in Ardabil based on the data of Iran's ministry of health. Collected information includes gender, age, age at disease onset, educational level and type of MS. We used Chi-squared test to analyze the relationship among variables and Logistic regression to estimate the odds ratio (OR) for individual variables, by SPSS software.
Results: The total number of patients was 800 with 564(70.5%) females, 236 (29.5%) males and the sex ratio of 2.38:1.The prevalence and incidence rate of MS was 62.16 and 7.61 per 100,000 in 2017.The prevalence was 89.43 and 35.95 per 100,000 in females and males respectively. The mean age at disease onset was 32.26±8.94 and there was no significant difference in the mean onset age between females and males. Totally 47(5.9%) patients experienced their first clinical attack before the age of 18. The relapsing-remitting(RR) form was the most prevalent type of MS (48.5%).The significant difference between females and males in MS types was observed (p value≤0.05). The secondary progressive(SP) form was higher in males (OR=1.76, CI=1.00-3.12).There was no significant association between MS type and education level.
Conclusions:The prevalence of MS is high in Ardabil. The most common type is RR form while male gender increases the risk of SP form .Our results also suggest a higher mean age of disease onset in Ardabil comparing other parts of Iran. Considering the different climate and environmental features of northwest of Iran, this can be a key to identify the related risk factors on the age of disease onset.
Disclosure: Negar Molazadeh: nothing to disclose
Sharareh Eskandarieh: nothing to disclose
Davar Altafi: nothing to disclose
Mohammad Ali Sahraian: nothing to disclose
Abstract: EP1348
Type: Poster Sessions
Abstract Category: Clinical aspects of MS - Epidemiology
Introduction:The epidemiology of Multiple Sclerosis (MS) in Ardabil, north-western region of Iran is unknown.
Aims: We aimed to design a study to evaluate the epidemiology of MS in Ardabil.
Methods: A retrospective population-based cross-sectional study was conducted from 2007 to 2017 in Ardabil based on the data of Iran's ministry of health. Collected information includes gender, age, age at disease onset, educational level and type of MS. We used Chi-squared test to analyze the relationship among variables and Logistic regression to estimate the odds ratio (OR) for individual variables, by SPSS software.
Results: The total number of patients was 800 with 564(70.5%) females, 236 (29.5%) males and the sex ratio of 2.38:1.The prevalence and incidence rate of MS was 62.16 and 7.61 per 100,000 in 2017.The prevalence was 89.43 and 35.95 per 100,000 in females and males respectively. The mean age at disease onset was 32.26±8.94 and there was no significant difference in the mean onset age between females and males. Totally 47(5.9%) patients experienced their first clinical attack before the age of 18. The relapsing-remitting(RR) form was the most prevalent type of MS (48.5%).The significant difference between females and males in MS types was observed (p value≤0.05). The secondary progressive(SP) form was higher in males (OR=1.76, CI=1.00-3.12).There was no significant association between MS type and education level.
Conclusions:The prevalence of MS is high in Ardabil. The most common type is RR form while male gender increases the risk of SP form .Our results also suggest a higher mean age of disease onset in Ardabil comparing other parts of Iran. Considering the different climate and environmental features of northwest of Iran, this can be a key to identify the related risk factors on the age of disease onset.
Disclosure: Negar Molazadeh: nothing to disclose
Sharareh Eskandarieh: nothing to disclose
Davar Altafi: nothing to disclose
Mohammad Ali Sahraian: nothing to disclose