Contributions
Abstract: EP1341
Type: Poster Sessions
Abstract Category: Clinical aspects of MS - Epidemiology
Introduction: Multiple sclerosis (MS) is among the leading causes of disability in Young Adults worldwide. Current estimates of MS burden in Eastern Mediterranean Region (EMR) are necessary for planning effective interventions.
Objectives: To estimate Prevalence, incidence, mortality, years lived with disability (YLDs), years of life lost (YLLs) and disability-adjusted life-years (DALYs) in EMR by country age, and sex from 1990 to 2016.
Aims: To inform healthcare professionals and decision making authorities of increasing MS burden.
Methods: We estimated regional and country-specific prevalence, incidence, mortality, DALYs, YLLs, and YLDs for MS. YLLs were computed by multiplying the number of deaths from MS in each age group by the reference life expectancy at the average of age of death among those who died in the age group. Prevalence of MS was multiplied by the disability weight for the corresponding health state to calculate YLDs. DALYs were computed as the sum of YLDs and YLLs.
Results: There was a rapid increase in the burden of MS in the region, it increased from 23,564 in 1990 to 71,775 in 2016 for males and 46,238 to 130,143 for females. Total DALYs in EMR countries was 12,810 in 1990 for males and increased to 36,391 in 2016 and from 18,962 to 53,851 for females. Lowest DALYs in both sexes were observed in Somalia (248) while the highest were in Iran (26,394). YLDs in males increased from 6,511 in 1990 to 19,515 in 2016, and in females from 12,247 to 33,937. The highest age-standardized prevalence, incidence, YLDs and DALYs were in Iran (72.11, 2.49, 18.03, and 32.5, respectively). The highest burden was among females and adults aged 30 to 45.
Conclusions: MS poses a significant public health problem in EMR region and prevalence rates have increased since 1990. Our findings provide valuable information to guide the development and implementation of measures to address the rising burden of MS in the region.
Disclosure: All authors declare no conflict of interest regarding this study.
Dr. Sahraian has received educational, research grants, lecture honorarium, travel supports to attend scientific meetings from Biogen‐Idec, Merck‐Serono, Bayer‐Schering, Novartis, Cinnagen, Osveh, Zistdaru, Zahravi, and Genzyme
Abstract: EP1341
Type: Poster Sessions
Abstract Category: Clinical aspects of MS - Epidemiology
Introduction: Multiple sclerosis (MS) is among the leading causes of disability in Young Adults worldwide. Current estimates of MS burden in Eastern Mediterranean Region (EMR) are necessary for planning effective interventions.
Objectives: To estimate Prevalence, incidence, mortality, years lived with disability (YLDs), years of life lost (YLLs) and disability-adjusted life-years (DALYs) in EMR by country age, and sex from 1990 to 2016.
Aims: To inform healthcare professionals and decision making authorities of increasing MS burden.
Methods: We estimated regional and country-specific prevalence, incidence, mortality, DALYs, YLLs, and YLDs for MS. YLLs were computed by multiplying the number of deaths from MS in each age group by the reference life expectancy at the average of age of death among those who died in the age group. Prevalence of MS was multiplied by the disability weight for the corresponding health state to calculate YLDs. DALYs were computed as the sum of YLDs and YLLs.
Results: There was a rapid increase in the burden of MS in the region, it increased from 23,564 in 1990 to 71,775 in 2016 for males and 46,238 to 130,143 for females. Total DALYs in EMR countries was 12,810 in 1990 for males and increased to 36,391 in 2016 and from 18,962 to 53,851 for females. Lowest DALYs in both sexes were observed in Somalia (248) while the highest were in Iran (26,394). YLDs in males increased from 6,511 in 1990 to 19,515 in 2016, and in females from 12,247 to 33,937. The highest age-standardized prevalence, incidence, YLDs and DALYs were in Iran (72.11, 2.49, 18.03, and 32.5, respectively). The highest burden was among females and adults aged 30 to 45.
Conclusions: MS poses a significant public health problem in EMR region and prevalence rates have increased since 1990. Our findings provide valuable information to guide the development and implementation of measures to address the rising burden of MS in the region.
Disclosure: All authors declare no conflict of interest regarding this study.
Dr. Sahraian has received educational, research grants, lecture honorarium, travel supports to attend scientific meetings from Biogen‐Idec, Merck‐Serono, Bayer‐Schering, Novartis, Cinnagen, Osveh, Zistdaru, Zahravi, and Genzyme