Contributions
Abstract: EP1339
Type: Poster Sessions
Abstract Category: Clinical aspects of MS - Natural course
Background: The outcome and prognosis of MS is unpredictable in nature. Famous scales are used to assess the outcome and impact of MS. The utility of several scales for predicting the outcome is limited. The aim of this study is to assess the outcome of MS in Saudi adult patients using validated scales.
Method: A single-centered, cross-sectional study at KAMC. All Saudi adult patients diagnosed with MS between 2000-2016 (269 patients) were included. Patients were contacted via phone-calls to assess their outcome using a newly developed and validated multi-component questionnaire. It included demographic data, disease course, and validated Arabic version of [Barthel Index (BI), Multiple Sclerosis Impact Scale (MSIS-29), Modified Rankin Scale (mRS) and EDSS].
Results: Out of 269 patients, 210 (78.2%) responded. The average patients' age was 37.44±10.3 years. The majority (69.5%) were females. 51(24.3%) patients reported worsening condition. Annually, the average relapse rate was 2.29±1.923. In regard to patients' outcome,120 (57.1%) showed no significant disability in mRS, 146 (69.5%) were ambulatory without aid in EDSS, and 96 (88.9%) patients were independent in BI score. The average of "Multiple Sclerosis Impact Scale" MSIS-29-PHYS score was 38.2±25.81 and MSIS-29-PSYCH score 33.6±27.6. MRS showed significant association with delayed diagnosis (P=0.025) and current use of DMT (P=0.002). EDSS also showed significant association with current use of DMT (P=0.042). BI showed significant association with medication compliance (P=0.044) and absence of attacks (P=0.054).
Conclusion: Majority of patients had favorable outcome which was linked significantly with the use of DMT, compliance, early diagnosis and absence of attacks. Further studies are recommended in larger sample size to examine the association of outcome with other factors.
Disclosure: authors have nothing to disclose
Abstract: EP1339
Type: Poster Sessions
Abstract Category: Clinical aspects of MS - Natural course
Background: The outcome and prognosis of MS is unpredictable in nature. Famous scales are used to assess the outcome and impact of MS. The utility of several scales for predicting the outcome is limited. The aim of this study is to assess the outcome of MS in Saudi adult patients using validated scales.
Method: A single-centered, cross-sectional study at KAMC. All Saudi adult patients diagnosed with MS between 2000-2016 (269 patients) were included. Patients were contacted via phone-calls to assess their outcome using a newly developed and validated multi-component questionnaire. It included demographic data, disease course, and validated Arabic version of [Barthel Index (BI), Multiple Sclerosis Impact Scale (MSIS-29), Modified Rankin Scale (mRS) and EDSS].
Results: Out of 269 patients, 210 (78.2%) responded. The average patients' age was 37.44±10.3 years. The majority (69.5%) were females. 51(24.3%) patients reported worsening condition. Annually, the average relapse rate was 2.29±1.923. In regard to patients' outcome,120 (57.1%) showed no significant disability in mRS, 146 (69.5%) were ambulatory without aid in EDSS, and 96 (88.9%) patients were independent in BI score. The average of "Multiple Sclerosis Impact Scale" MSIS-29-PHYS score was 38.2±25.81 and MSIS-29-PSYCH score 33.6±27.6. MRS showed significant association with delayed diagnosis (P=0.025) and current use of DMT (P=0.002). EDSS also showed significant association with current use of DMT (P=0.042). BI showed significant association with medication compliance (P=0.044) and absence of attacks (P=0.054).
Conclusion: Majority of patients had favorable outcome which was linked significantly with the use of DMT, compliance, early diagnosis and absence of attacks. Further studies are recommended in larger sample size to examine the association of outcome with other factors.
Disclosure: authors have nothing to disclose