Contributions
Abstract: EP1333
Type: Poster Sessions
Abstract Category: Clinical aspects of MS - Paediatric MS
Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system (CNS) in which a chronic demyelinating and inflammatory processes lead to damage of myelin sheaths of neurons and loss of axons. The appearance of various neurological symptoms are related to the location of focal CNS damage. First symptoms of the disease may develop suddenly or slowly. They could manifest as single or multifocal sensory symptoms (about 23%), motor symptoms (about 46%), disturbances of vision due to the optic neuritis (about 21%), hearing problems, brain stem symptoms (about 10%) or autonomic symptoms i.e. urinary problems, constipation (approx. 1%). Quite frequent are also transient paroxysmal symptoms i.e. Lhermitt's symptom, Uhthoff´s symptom.
Neurological manifestation may be accompanied by cognitive, psychiatric problems or chronic fatigue which were reported in few reports (Zarei et al. 2003, Habek et al. 2005; Staff et al. 2009, Coebergh et al.2010, Assaouad et al. 2014; Berna et al 2016; Zambon et al. 2017; Amato et al. 2017).
The authors present pediatric patients with isolated cognitive impairment or psychiatric symptoms as the first manifestation of the MS in children preceding typical neurological symptoms. Its subsequent recognition is very important for diagnosis of MS and quick implementation of proper treatment .
Disclosure: The authors have any potential conflict of interest
Małgorzata Bilska: nothing to disclose
Sergiusz Jóźwiak: nothing to disclose
Michał Ciastoń: nothing to disclose
Łukasz Dropczyński: nothing to disclose
Abstract: EP1333
Type: Poster Sessions
Abstract Category: Clinical aspects of MS - Paediatric MS
Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system (CNS) in which a chronic demyelinating and inflammatory processes lead to damage of myelin sheaths of neurons and loss of axons. The appearance of various neurological symptoms are related to the location of focal CNS damage. First symptoms of the disease may develop suddenly or slowly. They could manifest as single or multifocal sensory symptoms (about 23%), motor symptoms (about 46%), disturbances of vision due to the optic neuritis (about 21%), hearing problems, brain stem symptoms (about 10%) or autonomic symptoms i.e. urinary problems, constipation (approx. 1%). Quite frequent are also transient paroxysmal symptoms i.e. Lhermitt's symptom, Uhthoff´s symptom.
Neurological manifestation may be accompanied by cognitive, psychiatric problems or chronic fatigue which were reported in few reports (Zarei et al. 2003, Habek et al. 2005; Staff et al. 2009, Coebergh et al.2010, Assaouad et al. 2014; Berna et al 2016; Zambon et al. 2017; Amato et al. 2017).
The authors present pediatric patients with isolated cognitive impairment or psychiatric symptoms as the first manifestation of the MS in children preceding typical neurological symptoms. Its subsequent recognition is very important for diagnosis of MS and quick implementation of proper treatment .
Disclosure: The authors have any potential conflict of interest
Małgorzata Bilska: nothing to disclose
Sergiusz Jóźwiak: nothing to disclose
Michał Ciastoń: nothing to disclose
Łukasz Dropczyński: nothing to disclose