Contributions
Abstract: EP1315
Type: Poster Sessions
Abstract Category: Clinical aspects of MS - MS Variants
Introduction: Multiple sclerosis is a neurodegenerative disease of the central nervous system resulting from the combination of various complex etiological mechanisms (viral, genetic, vitamin D deficiency ...). The forms of familial MS represent 10-15%
Study aim: To describe the clinical aspects and the evolutionary profile of the familial forms of MS
Patients and method: Retrospective descriptive study of the forms of familial MS in the neurology department, Ibn Rochd university hospital of Casablanca. We report the case of 4 families of which at least 2 members are suffering from the disease.
Results: Families with 2 affected members had a 2nd degree relationship and 1st and 2nd degree in families with more than 2 affected subjects. The average age at symptoms' onset was 27.83 years with a sex ratio (female /male) of 1.5
The remitting form represented 85.71%. Oligoclonal bands were found only in 25% of patients.
Discussion: Genetic susceptibility in multiple sclerosis has already been clearly defined
And this was initially suggested by the increased incidence of the disease in some families. The oligoclonal bands were only found in 25% of cases, in contrast to sporadic MS.
Conclusion: It shows from this first analysis that the remitting forms dominate the clinical presentation and that the oligoclonal bands are often negative in the CSF.
Disclosure: Nothing to disclose
Abstract: EP1315
Type: Poster Sessions
Abstract Category: Clinical aspects of MS - MS Variants
Introduction: Multiple sclerosis is a neurodegenerative disease of the central nervous system resulting from the combination of various complex etiological mechanisms (viral, genetic, vitamin D deficiency ...). The forms of familial MS represent 10-15%
Study aim: To describe the clinical aspects and the evolutionary profile of the familial forms of MS
Patients and method: Retrospective descriptive study of the forms of familial MS in the neurology department, Ibn Rochd university hospital of Casablanca. We report the case of 4 families of which at least 2 members are suffering from the disease.
Results: Families with 2 affected members had a 2nd degree relationship and 1st and 2nd degree in families with more than 2 affected subjects. The average age at symptoms' onset was 27.83 years with a sex ratio (female /male) of 1.5
The remitting form represented 85.71%. Oligoclonal bands were found only in 25% of patients.
Discussion: Genetic susceptibility in multiple sclerosis has already been clearly defined
And this was initially suggested by the increased incidence of the disease in some families. The oligoclonal bands were only found in 25% of cases, in contrast to sporadic MS.
Conclusion: It shows from this first analysis that the remitting forms dominate the clinical presentation and that the oligoclonal bands are often negative in the CSF.
Disclosure: Nothing to disclose