ECTRIMS eLearning

Clinical and urodynamic risk factors for recurrent urinary tract infections in multiple sclerosis
Author(s): ,
P. Montero-Escribano
Affiliations:
Hospital Clinico San Carlos, Madrid, Spain
,
J.A. Matias-Guiu
Affiliations:
Hospital Clinico San Carlos, Madrid, Spain
,
V. Pytel
Affiliations:
Hospital Clinico San Carlos, Madrid, Spain
,
E. Lopez
Affiliations:
Hospital Clinico San Carlos, Madrid, Spain
,
M. Vírseda
Affiliations:
Hospital Clinico San Carlos, Madrid, Spain
,
M. Esteban
Affiliations:
Hospital Clinico San Carlos, Madrid, Spain
,
J. Moreno
Affiliations:
Hospital Clinico San Carlos, Madrid, Spain
J. Matias-Guiu
Affiliations:
Hospital Clinico San Carlos, Madrid, Spain
ECTRIMS Learn. Montero-Escribano P. 10/11/18; 228540; P696
Paloma Montero-Escribano
Paloma Montero-Escribano
Contributions
Abstract

Abstract: P696

Type: Poster Sessions

Abstract Category: Clinical aspects of MS - MS symptoms

Background: More than 70% (depending on clinical characteristics) of patients with multiple sclerosis (MS) develop urinary changes during the disease. Knowledge of the mechanisms of urinary tract infections in MS can contribute to a better approach to these patients and increase their prognosis and quality of life.
Methods: A total of 115 patients with MS and urinary disorders were studied. Demographic and clinical data were collected. A complete urodynamic study was performed in accordance with the specifications of the International Contience Society and the protocols of the Good Urodynamic Practice.
Results: Stress urinary incontinence (SUI) was demonstrated in 23 patients (20%). Selective electromyography (EMG) showed the existence of Superior Motor Neurone-type neurogenic dysfunction in 63 patients (55%), Lower Motor Neurone-type in 13 patients (11%) and EMG characteristics and both types in 2 patients (2%). a higher frequency of rUTIs in relation to the longer LUTS evolution time, although not by type, in relation to the MS evolution time, and also with the higher EDSS score. Also, the presence of rUTIs was more frequent in the progressive forms (SPMS and PPMS) compared to patients with RRMS forms. No increased rUTI frequency was found associated with the use of intermittent bladder catheterization.
Disclosure: The severity of the disability measured by the EDSS, the time of progression and the clinical form of the disease are the main risk factors for the development of recurrent urinary tract infections (RUTIs) in patients with multiple sclerosis.
The main urodynamic parameters associated with rUTIs are those that reflect a lower detrusor contractile capacity. Neurogenic disfunction of the lower urinary tract, does not increase the risk.

Abstract: P696

Type: Poster Sessions

Abstract Category: Clinical aspects of MS - MS symptoms

Background: More than 70% (depending on clinical characteristics) of patients with multiple sclerosis (MS) develop urinary changes during the disease. Knowledge of the mechanisms of urinary tract infections in MS can contribute to a better approach to these patients and increase their prognosis and quality of life.
Methods: A total of 115 patients with MS and urinary disorders were studied. Demographic and clinical data were collected. A complete urodynamic study was performed in accordance with the specifications of the International Contience Society and the protocols of the Good Urodynamic Practice.
Results: Stress urinary incontinence (SUI) was demonstrated in 23 patients (20%). Selective electromyography (EMG) showed the existence of Superior Motor Neurone-type neurogenic dysfunction in 63 patients (55%), Lower Motor Neurone-type in 13 patients (11%) and EMG characteristics and both types in 2 patients (2%). a higher frequency of rUTIs in relation to the longer LUTS evolution time, although not by type, in relation to the MS evolution time, and also with the higher EDSS score. Also, the presence of rUTIs was more frequent in the progressive forms (SPMS and PPMS) compared to patients with RRMS forms. No increased rUTI frequency was found associated with the use of intermittent bladder catheterization.
Disclosure: The severity of the disability measured by the EDSS, the time of progression and the clinical form of the disease are the main risk factors for the development of recurrent urinary tract infections (RUTIs) in patients with multiple sclerosis.
The main urodynamic parameters associated with rUTIs are those that reflect a lower detrusor contractile capacity. Neurogenic disfunction of the lower urinary tract, does not increase the risk.

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