Contributions
Abstract: P522
Type: Poster Sessions
Abstract Category: Pathology and pathogenesis of MS - Neuropsychology
Background: there is some evidences that Cognitive Behavioural Therapy (CBT) can be an effective treatment for mood disorders in Multiple Sclerosis (MS). Several studies suggest that some methods of the third wave of CBT could improve cognitive performance in others populations. Taking this into account, we designed and evaluated the efficacy of a CBT program to reduce mood disorders and cognitive impairments in MS.
Method: 120 patients with relapsing forms of MS were randomly assigned to CBT therapy (n=40), psychophysiological training (PT) (n=40) or wait list control condition (n=40). Both treatments consisted of 14 weekly 1.5-hour group sessions with post-intervention assessment one week after the end of training. Outcomes included anxiety, depression and neuropsychological impairments. Assessment measures: Hospital Anxiety and Depression Scale (HADS); Multiple Sclerosis Neuropsychological Questionnaire (MSNQ); Multiple Sclerosis Quality of Life-54 (MSQOL-54); Cognitive Triad Inventory (CTI); Brief Repeatable Battery of Neuropsychological Test (BRB-N).
Results: discriminant analysis over gain scores (post-intervention minus pre-intervention) showed a significant function [λ =0,73, F(2,81)=13,54; p< 0,0001]. This function clearly separates CBT group from PT and control groups, revealing the most important variables for group differences: Symbol Digit Modalities Test (SDMT), Paced Auditory Serial Addition Test (PASAT), MSQOL-54, MSNQ, HADS, CTI.
Conclusions: the findings here reported allow us to conclude that the application of the CBT was particularly effective in improving emotional distress and cognitive functions in MS.
Disclosure: Study Group: nothing to disclose.
Abstract: P522
Type: Poster Sessions
Abstract Category: Pathology and pathogenesis of MS - Neuropsychology
Background: there is some evidences that Cognitive Behavioural Therapy (CBT) can be an effective treatment for mood disorders in Multiple Sclerosis (MS). Several studies suggest that some methods of the third wave of CBT could improve cognitive performance in others populations. Taking this into account, we designed and evaluated the efficacy of a CBT program to reduce mood disorders and cognitive impairments in MS.
Method: 120 patients with relapsing forms of MS were randomly assigned to CBT therapy (n=40), psychophysiological training (PT) (n=40) or wait list control condition (n=40). Both treatments consisted of 14 weekly 1.5-hour group sessions with post-intervention assessment one week after the end of training. Outcomes included anxiety, depression and neuropsychological impairments. Assessment measures: Hospital Anxiety and Depression Scale (HADS); Multiple Sclerosis Neuropsychological Questionnaire (MSNQ); Multiple Sclerosis Quality of Life-54 (MSQOL-54); Cognitive Triad Inventory (CTI); Brief Repeatable Battery of Neuropsychological Test (BRB-N).
Results: discriminant analysis over gain scores (post-intervention minus pre-intervention) showed a significant function [λ =0,73, F(2,81)=13,54; p< 0,0001]. This function clearly separates CBT group from PT and control groups, revealing the most important variables for group differences: Symbol Digit Modalities Test (SDMT), Paced Auditory Serial Addition Test (PASAT), MSQOL-54, MSNQ, HADS, CTI.
Conclusions: the findings here reported allow us to conclude that the application of the CBT was particularly effective in improving emotional distress and cognitive functions in MS.
Disclosure: Study Group: nothing to disclose.