Contributions
Abstract: P365
Type: Poster Sessions
Abstract Category: Clinical aspects of MS - Epidemiology
Background: Diet may be relevant in multiple sclerosis (MS) onset and progression.
Objectives: To examine dietary patterns in a cohort of participants in the first five years following symptom onset.
Methods: We used the Cancer Council Victoria Food Frequency Questionnaire to evaluate dietary intake at baseline and 5-year review in a cohort of participants (n=260) in the early stages of CNS demyelination. Using iterated principal factor analysis, dietary patterns were identified and determinants thereof evaluated using linear regression.
Results: Three reproducible dietary patterns which we labelled 'Western', 'Mixed' and 'Prudent' were independently found at baseline and 5-year reviews, these patterns explaining 42.5% & 41.4, 32.0% & 29.1%, and 30.2% & 37.6% at baseline and 5-year reviews, respectively. The Western pattern was positively influenced by processed meats, takeaway, fried foods, confectionary, beer and spirits. The Mixed pattern was positively influenced by fried and sweet foods and some vegetables. The Prudent pattern loaded positively on whole-grains, non-fried fish, some vegetables, fresh fruits and wine. Those who were overweight or were current smokers had on average a higher Western diet score, whereas females and those who were middle-aged had a lower Western Score. Those using omega-3/6 containing supplements, middle-aged adults and those most physically active had higher Prudent diet scores. During follow-up, the Western and Mixed diet pattern scores decreased, whereas Prudent diet pattern scores increased. The change in Western diet score was significantly lower among females and those who decreased their BMI, whereas the change in Prudent diet score was significantly less among those who were current smokers at baseline or who increased their BMI.
Conclusion: Although all three dietary patterns persisted during follow-up, there was evidence that some participants improved their diet whereas others did not. These findings have implications for the health improvement efforts of people in the early stages of living with MS.
Disclosure: The Ausimmune and AusLong Studies were funded by the National Multiple Sclerosis Society of the United States of America (award RG3364A1/2) and the National Health and Medical Research Council of Australia (APP316901 and 224215).
The members of the Ausimmune/AusLong Investigators Group are as follows: Robyn M Lucas (National Centre for Epidemiology and Population Health, Canberra), Keith Dear (University of Adelaide, Australia), Anne-Louise Ponsonby and Terry Dwyer (Murdoch Childrens Research Institute, Melbourne, Australia), Ingrid van der Mei, Leigh Blizzard, Steve Simpson, Jr. and Bruce V Taylor (Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia), Simon Broadley (School of Medicine, Griffith University, Gold Coast Campus, Australia), Trevor Kilpatrick (Centre for Neurosciences, Department of Anatomy and Neuroscience, University of Melbourne, Melbourne, Australia). David Williams and Jeanette Lechner-Scott (University of Newcastle, Newcastle, Australia), Cameron Shaw and Caron Chapman (Barwon Health, Geelong, Australia), Alan Coulthard (University of Queensland, Brisbane, Australia), Michael P Pender (The University of Queensland, Brisbane, Australia) and Patricia Valery (QIMR Berghofer Medical Research Institute, Brisbane, Australia).
Abstract: P365
Type: Poster Sessions
Abstract Category: Clinical aspects of MS - Epidemiology
Background: Diet may be relevant in multiple sclerosis (MS) onset and progression.
Objectives: To examine dietary patterns in a cohort of participants in the first five years following symptom onset.
Methods: We used the Cancer Council Victoria Food Frequency Questionnaire to evaluate dietary intake at baseline and 5-year review in a cohort of participants (n=260) in the early stages of CNS demyelination. Using iterated principal factor analysis, dietary patterns were identified and determinants thereof evaluated using linear regression.
Results: Three reproducible dietary patterns which we labelled 'Western', 'Mixed' and 'Prudent' were independently found at baseline and 5-year reviews, these patterns explaining 42.5% & 41.4, 32.0% & 29.1%, and 30.2% & 37.6% at baseline and 5-year reviews, respectively. The Western pattern was positively influenced by processed meats, takeaway, fried foods, confectionary, beer and spirits. The Mixed pattern was positively influenced by fried and sweet foods and some vegetables. The Prudent pattern loaded positively on whole-grains, non-fried fish, some vegetables, fresh fruits and wine. Those who were overweight or were current smokers had on average a higher Western diet score, whereas females and those who were middle-aged had a lower Western Score. Those using omega-3/6 containing supplements, middle-aged adults and those most physically active had higher Prudent diet scores. During follow-up, the Western and Mixed diet pattern scores decreased, whereas Prudent diet pattern scores increased. The change in Western diet score was significantly lower among females and those who decreased their BMI, whereas the change in Prudent diet score was significantly less among those who were current smokers at baseline or who increased their BMI.
Conclusion: Although all three dietary patterns persisted during follow-up, there was evidence that some participants improved their diet whereas others did not. These findings have implications for the health improvement efforts of people in the early stages of living with MS.
Disclosure: The Ausimmune and AusLong Studies were funded by the National Multiple Sclerosis Society of the United States of America (award RG3364A1/2) and the National Health and Medical Research Council of Australia (APP316901 and 224215).
The members of the Ausimmune/AusLong Investigators Group are as follows: Robyn M Lucas (National Centre for Epidemiology and Population Health, Canberra), Keith Dear (University of Adelaide, Australia), Anne-Louise Ponsonby and Terry Dwyer (Murdoch Childrens Research Institute, Melbourne, Australia), Ingrid van der Mei, Leigh Blizzard, Steve Simpson, Jr. and Bruce V Taylor (Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia), Simon Broadley (School of Medicine, Griffith University, Gold Coast Campus, Australia), Trevor Kilpatrick (Centre for Neurosciences, Department of Anatomy and Neuroscience, University of Melbourne, Melbourne, Australia). David Williams and Jeanette Lechner-Scott (University of Newcastle, Newcastle, Australia), Cameron Shaw and Caron Chapman (Barwon Health, Geelong, Australia), Alan Coulthard (University of Queensland, Brisbane, Australia), Michael P Pender (The University of Queensland, Brisbane, Australia) and Patricia Valery (QIMR Berghofer Medical Research Institute, Brisbane, Australia).