Contributions
Abstract: EP1837
Type: ePoster
Abstract Category: Therapy - symptomatic - 34 Quality of life
Background: Patients with multiple sclerosis (MS) often suffer from various impairments in gait leading to decrease in walking distance and velocity. Physical rehabilitation in accordance is aimed to improve gait and promote walking practice. To establish effective walking practice, it is of importance to measure oxygen uptake (VO2) during walking at a given speed and calculate energy cost of walking (CoW).
Objective: To determine whether the energy expenditure during walking at different speeds (normal and fast) in MS patients is related to neurological disability as assessed by the EDSS.
Methods: Energy expenditure was measured during normal and fast walking in ambulatory multiple sclerosis (MS) patients with EDSS ≤ 4.5. Gas exchange values were acquired continuously by open spirometry and indirect calorimetry using a portable metabolic device (COSMED K5, It). Oxygen consumption at rest was calculated by averaging 30-second oxygen uptake (VO2) values over a 5-minutr period of seated rest. Participants then performed normal speed and fast speed walking trials, each continuously for 6 minutes along an indoor 30m corridor. O2cost (ml/Kg*m) was extracted for each speed gait indicating the amount of energy needed to walk one meter was assessed.
Results: 60 consecutive MS patients, 32 females, 28 males, mean±SD age 38.2±13.9 years, disease duration 5.9±8.5 years, EDSS 2.2±1.3, BMI 25.1±4.7 were included in the study. Energy expenditure at normal walking was 0.191±0.052 and increased during fast walking to 0.207±0.06. Analysis of energy expenditure both in normal and fast walking was significantly different between patients with EDSS ≤ 2.5 (N=47) and patients with EDSS range between 3.0 to 4.5 (N=13), p=0.006 and p=0.002, respectively.
Conclusion: Gait energetic costs of normal and fast walking increase with metrological disability.
Disclosure: All author Declare no conflict of interest
Abstract: EP1837
Type: ePoster
Abstract Category: Therapy - symptomatic - 34 Quality of life
Background: Patients with multiple sclerosis (MS) often suffer from various impairments in gait leading to decrease in walking distance and velocity. Physical rehabilitation in accordance is aimed to improve gait and promote walking practice. To establish effective walking practice, it is of importance to measure oxygen uptake (VO2) during walking at a given speed and calculate energy cost of walking (CoW).
Objective: To determine whether the energy expenditure during walking at different speeds (normal and fast) in MS patients is related to neurological disability as assessed by the EDSS.
Methods: Energy expenditure was measured during normal and fast walking in ambulatory multiple sclerosis (MS) patients with EDSS ≤ 4.5. Gas exchange values were acquired continuously by open spirometry and indirect calorimetry using a portable metabolic device (COSMED K5, It). Oxygen consumption at rest was calculated by averaging 30-second oxygen uptake (VO2) values over a 5-minutr period of seated rest. Participants then performed normal speed and fast speed walking trials, each continuously for 6 minutes along an indoor 30m corridor. O2cost (ml/Kg*m) was extracted for each speed gait indicating the amount of energy needed to walk one meter was assessed.
Results: 60 consecutive MS patients, 32 females, 28 males, mean±SD age 38.2±13.9 years, disease duration 5.9±8.5 years, EDSS 2.2±1.3, BMI 25.1±4.7 were included in the study. Energy expenditure at normal walking was 0.191±0.052 and increased during fast walking to 0.207±0.06. Analysis of energy expenditure both in normal and fast walking was significantly different between patients with EDSS ≤ 2.5 (N=47) and patients with EDSS range between 3.0 to 4.5 (N=13), p=0.006 and p=0.002, respectively.
Conclusion: Gait energetic costs of normal and fast walking increase with metrological disability.
Disclosure: All author Declare no conflict of interest