Contributions
Abstract: EP1612
Type: ePoster
Abstract Category: Pathology and pathogenesis of MS - 25 Biomarkers
The Observatoire Français de la Sclérose En Plaques (OFSEP) is a French national cohort of patients with multiple sclerosis (MS), granted in 2011 for a ten-year tenure by the French National Research Agency. The OFSEP's biobank aims to provide research high quality biological samples from MS patients, associated to clinical data.
Selected groups of patients only are currently sampled: Clinical Isolated Syndromes (CIS), Radiologically Isolated Syndromes (RIS), primary progressive MS (PPMS), NeuroMyelitis Optica Spectrum Disorders (NMOSD), Acute Disseminated EncephaloMyelitis (ADEM) and multifocal leukoencephalopathy (PML). Blood and urine collection are mandatory, CSF and stool are optional.
To achieve high quality samples, OFSEP relies on 13 French biobanks certified with the NF S96-900 norm.
Samples of serum, plasma, DNA, PBMC (Peripheral Blood Mononuclear Cells), urine, CSF, CSF cells and stool are conditioned in sterile conditions and rapidly stored in a highly secured manner. According with international recommendations, delay between sampling and freezing is less than 4h (24h for PBMC).
More than 15 000 biological samples are now available for MS research, corresponding to 241 CIS patients, 36 RIS patients, 108 PPMS patients, 148 NMOSD patients, 11 patients with ADEM and 4 PML. Diagnosis and respect of inclusion criteria were controlled by using EDMUS clinical data and when necessary by expert groups (RIS and NMOSD).
OFSEP's biobank associated with clinical data from EDMUS software provides the opportunity to achieve high level research on MS biomarkers. Biological samples and associated data are open to academic and industrial research. In a near future, collection will extend to relapsing-remitting and atypical forms of MS.
Disclosure:
Nathalie Dufay, Romain Casey, Benjamin Britsch-Fayet, Sylvain Lehman, Géraldine Gallot, Patrick Gelé, Bertrand Fontaine, Eric Thouvenot, Romain Marignier, Hélène Zephir and David Laplaud: nothing to disclose
Abstract: EP1612
Type: ePoster
Abstract Category: Pathology and pathogenesis of MS - 25 Biomarkers
The Observatoire Français de la Sclérose En Plaques (OFSEP) is a French national cohort of patients with multiple sclerosis (MS), granted in 2011 for a ten-year tenure by the French National Research Agency. The OFSEP's biobank aims to provide research high quality biological samples from MS patients, associated to clinical data.
Selected groups of patients only are currently sampled: Clinical Isolated Syndromes (CIS), Radiologically Isolated Syndromes (RIS), primary progressive MS (PPMS), NeuroMyelitis Optica Spectrum Disorders (NMOSD), Acute Disseminated EncephaloMyelitis (ADEM) and multifocal leukoencephalopathy (PML). Blood and urine collection are mandatory, CSF and stool are optional.
To achieve high quality samples, OFSEP relies on 13 French biobanks certified with the NF S96-900 norm.
Samples of serum, plasma, DNA, PBMC (Peripheral Blood Mononuclear Cells), urine, CSF, CSF cells and stool are conditioned in sterile conditions and rapidly stored in a highly secured manner. According with international recommendations, delay between sampling and freezing is less than 4h (24h for PBMC).
More than 15 000 biological samples are now available for MS research, corresponding to 241 CIS patients, 36 RIS patients, 108 PPMS patients, 148 NMOSD patients, 11 patients with ADEM and 4 PML. Diagnosis and respect of inclusion criteria were controlled by using EDMUS clinical data and when necessary by expert groups (RIS and NMOSD).
OFSEP's biobank associated with clinical data from EDMUS software provides the opportunity to achieve high level research on MS biomarkers. Biological samples and associated data are open to academic and industrial research. In a near future, collection will extend to relapsing-remitting and atypical forms of MS.
Disclosure:
Nathalie Dufay, Romain Casey, Benjamin Britsch-Fayet, Sylvain Lehman, Géraldine Gallot, Patrick Gelé, Bertrand Fontaine, Eric Thouvenot, Romain Marignier, Hélène Zephir and David Laplaud: nothing to disclose