Contributions
Abstract: EP1590
Type: ePoster
Abstract Category: Pathology and pathogenesis of MS - 24 Neuropsychology
Introduction: Cognitive disorders are common in Multiple Sclerosis (MS) and can be present at any stage of the disease, affecting attention, concentration, planning, memory. Their functional impact can alter quality of life. They are often associated with confounding factors: fatigue, anxiety, depression. The question of the optimal time for a more complete neuropsychological assessment remains to be asked, this assessment being most often carried out before a spontaneous cognitive complaint with the difficulty of determining the weight of any associated factors.
Objectives: The aim was to assess the feasibility and relevance of a rapid, comprehensive and functional cognitive screening battery, which could be carried out during an usual consultation.
Methods: 73 MS patients reporting a cognitive complaint benefited from cognitive explorations. Seven themes were studied through Visual Analogue Scales (VAS), quantified on 10 points: fatigue, fitness, pain, thymic state, attention, memory, organization. The cognitive study involved the realization of the SDMT and the story of Barbizet, completed by a fatigue scale (FSS score) and an anxiety and depression scale (HADS).
Results: A good feasibility of the evaluation was validated with a duration of 15 to 20 minutes, allowing a realization in common practice. Among the different dimensions explored through the VAS, a score>5 was identified for fatigue, fitness and memory. Fatigue was also underlined by the average FSS score (5.1/7). The HADS did not appear pathological. As for the analytical evaluation, the mean score of SDMT was pathological at 38.9 (SD:13.6). The story of Barbizet showed an average score of 11.3 (SD:4.4). Interestingly, double dissociation was found for some patients between SDMT and recall performances, proving interest of both tests. Spearman´s correlation found a modest correlation for pain, memory, state of mood and organization; on the contrary, the use of a purely analytical balance appeared insufficient. These results underline the value of jointly realizing these personal feelings scales and cognitive tests.
Conclusion: This work validates the use of a simple and reproducible tool in common consultation, in the detection of cognitive disorders and possible confounding factors, in the MS patients. These tests allow to refer patients for further explorations, to adjust the management of confounding factors and thus to optimize the management, in particular for fatigue and anxiety.
Disclosure: Any disclosure for this work.
Abstract: EP1590
Type: ePoster
Abstract Category: Pathology and pathogenesis of MS - 24 Neuropsychology
Introduction: Cognitive disorders are common in Multiple Sclerosis (MS) and can be present at any stage of the disease, affecting attention, concentration, planning, memory. Their functional impact can alter quality of life. They are often associated with confounding factors: fatigue, anxiety, depression. The question of the optimal time for a more complete neuropsychological assessment remains to be asked, this assessment being most often carried out before a spontaneous cognitive complaint with the difficulty of determining the weight of any associated factors.
Objectives: The aim was to assess the feasibility and relevance of a rapid, comprehensive and functional cognitive screening battery, which could be carried out during an usual consultation.
Methods: 73 MS patients reporting a cognitive complaint benefited from cognitive explorations. Seven themes were studied through Visual Analogue Scales (VAS), quantified on 10 points: fatigue, fitness, pain, thymic state, attention, memory, organization. The cognitive study involved the realization of the SDMT and the story of Barbizet, completed by a fatigue scale (FSS score) and an anxiety and depression scale (HADS).
Results: A good feasibility of the evaluation was validated with a duration of 15 to 20 minutes, allowing a realization in common practice. Among the different dimensions explored through the VAS, a score>5 was identified for fatigue, fitness and memory. Fatigue was also underlined by the average FSS score (5.1/7). The HADS did not appear pathological. As for the analytical evaluation, the mean score of SDMT was pathological at 38.9 (SD:13.6). The story of Barbizet showed an average score of 11.3 (SD:4.4). Interestingly, double dissociation was found for some patients between SDMT and recall performances, proving interest of both tests. Spearman´s correlation found a modest correlation for pain, memory, state of mood and organization; on the contrary, the use of a purely analytical balance appeared insufficient. These results underline the value of jointly realizing these personal feelings scales and cognitive tests.
Conclusion: This work validates the use of a simple and reproducible tool in common consultation, in the detection of cognitive disorders and possible confounding factors, in the MS patients. These tests allow to refer patients for further explorations, to adjust the management of confounding factors and thus to optimize the management, in particular for fatigue and anxiety.
Disclosure: Any disclosure for this work.