Contributions
Abstract: EP1585
Type: ePoster
Abstract Category: Pathology and pathogenesis of MS - 24 Neuropsychology
Objectives: Cognitive impairment is recognized as a core feature of multiple sclerosis (MS).Mostly memory, attention, and executive functions are affected.This study aims to compare visual information processing between multiple sclerosis(MS) patients and controls.
Methods: A case-control study was conducted in 30 MS patients(22female) and 30 (21female) age-, gender- and education level-matched healty subjects.All subjects were administered a detailed neuropsychological evaluation. Visuospatial information processing was evaluated with Hooper visual organization test (VOT),that requires perceptual and mental reorganization of parts of an object into an identifiable whole. The patients and controls were also administered Beck Depression Inventory and Mini-MentalState Examination.
Results: Patient and control groups did not differ in means of gender, age and education levels.BDI scores were similar in both groups and general cognitive functioning of patients were much the same.
MS subjects performed more poorly on the TMT part A and B than the control group.Mean scores obtained in PASAT were also lower in MS patients in comparison to healthy subjects.Visual perceptual organization ability of multiple sclerosis patients were much the same as controls' (MS:22.0+4.1,Control:23.6+2.7;p=0.080).In order to evaluate whether the progressing age does load any burden to visual perception organization ability, patient and control groups were categorized into three age groups(those younger than 25 years old, those between 25-35 years old, and those older than 35 years).Though, healthy controls showed no statistically significant difference between groups(F=1.559;p=0.229); a significant difference was observed in MS group (F=4.670;p=0.018). Especially those older than 35 years had a poor performance in comparison to younger patients. VOT performance showed a moderate inverse correlation with disease duration and total attack number(r:-0.471,p=0.009;r:-0.451,p=0.012;respectively) but no significant correlation with EDSS(r:-0.276;p=0.140). VOT performance correlated moderately with PASAT score(r:0.529;p=0.005) and showed an inverse correlation with TMA-A,-Bscores(r:-0.535,p=0.002;r:-0.421,p=0.021; respectively).
Conclusions: Visual information processing ability is unimpaired in MS patients.
Disclosure: Serpil Demirci:nothing to disclose
Abstract: EP1585
Type: ePoster
Abstract Category: Pathology and pathogenesis of MS - 24 Neuropsychology
Objectives: Cognitive impairment is recognized as a core feature of multiple sclerosis (MS).Mostly memory, attention, and executive functions are affected.This study aims to compare visual information processing between multiple sclerosis(MS) patients and controls.
Methods: A case-control study was conducted in 30 MS patients(22female) and 30 (21female) age-, gender- and education level-matched healty subjects.All subjects were administered a detailed neuropsychological evaluation. Visuospatial information processing was evaluated with Hooper visual organization test (VOT),that requires perceptual and mental reorganization of parts of an object into an identifiable whole. The patients and controls were also administered Beck Depression Inventory and Mini-MentalState Examination.
Results: Patient and control groups did not differ in means of gender, age and education levels.BDI scores were similar in both groups and general cognitive functioning of patients were much the same.
MS subjects performed more poorly on the TMT part A and B than the control group.Mean scores obtained in PASAT were also lower in MS patients in comparison to healthy subjects.Visual perceptual organization ability of multiple sclerosis patients were much the same as controls' (MS:22.0+4.1,Control:23.6+2.7;p=0.080).In order to evaluate whether the progressing age does load any burden to visual perception organization ability, patient and control groups were categorized into three age groups(those younger than 25 years old, those between 25-35 years old, and those older than 35 years).Though, healthy controls showed no statistically significant difference between groups(F=1.559;p=0.229); a significant difference was observed in MS group (F=4.670;p=0.018). Especially those older than 35 years had a poor performance in comparison to younger patients. VOT performance showed a moderate inverse correlation with disease duration and total attack number(r:-0.471,p=0.009;r:-0.451,p=0.012;respectively) but no significant correlation with EDSS(r:-0.276;p=0.140). VOT performance correlated moderately with PASAT score(r:0.529;p=0.005) and showed an inverse correlation with TMA-A,-Bscores(r:-0.535,p=0.002;r:-0.421,p=0.021; respectively).
Conclusions: Visual information processing ability is unimpaired in MS patients.
Disclosure: Serpil Demirci:nothing to disclose