Contributions
Abstract: EP1584
Type: ePoster
Abstract Category: Pathology and pathogenesis of MS - 24 Neuropsychology
Background: The Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) is an international assessment tool for monitoring cognitive function in multiple sclerosis (MS) patients. BICAMS consist of three tests: the Symbol Digit Modalities Test (SDMT), the California Verbal Learning Test - Second Edition (CVLT II) and the Brief Visuospatial Memory Test - Revised (BVMT-R). Our objective was to validate and assess the reliability of BICAMS to obtain normative data in Portuguese population.
Method: The sample composed of 107 MS patients and 62 healthy controls (HC). In order to test its reliability, BICAMS was re-administered in a subset of 25 patients after 3 month later. Depression, anxiety and fatigue were assessed by Hospital Anxiety and Depression Scale and Modified Fatigue Impact Scale (MFIS).
Results: The sample comprises a control group (n=62, age: M = 37,00; DP = 12,74, education:
M = 14,53; DP = 3,44) and a clinical group (n=107, age: M = 38,50; DP = 11,34, education: M = 13,51; DP = 3,82). About 64% of the participants were women. The groups did not differ for age, education,
or gender. The MS group performed significantly worse than the control group across the three neuropsychological tests, yielding the following values: SDMT: t(167) = 3.71, p = .000; CVLT-II: t(167) = 2.69, p = .008; and BVMT-R: t(167) = 2.33, p = .021. The mean raw scores for Portuguese normative data were as follows: SDMT: 58.18 ± 10.25; CVLT-II: 59.65 ± 10.96; and BVMT-R: 24.05 ± 6.47. Finally, test-retest reliability coefficients for each test were as follows: SDMT: r = .92; CVLT-II: r = .48; and BVMT-R: r = .86.
Conclusion: This BICAMS version is reliable and useful as a monitoring tool for identifying MS patients with cognitive impairment.
Disclosure:
Funding: This project was partially funded by a research grant from Bayer AG. The authors would like to thank Dr. Dawn Langdon for her advice and support during the course of this study.
Abstract: EP1584
Type: ePoster
Abstract Category: Pathology and pathogenesis of MS - 24 Neuropsychology
Background: The Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) is an international assessment tool for monitoring cognitive function in multiple sclerosis (MS) patients. BICAMS consist of three tests: the Symbol Digit Modalities Test (SDMT), the California Verbal Learning Test - Second Edition (CVLT II) and the Brief Visuospatial Memory Test - Revised (BVMT-R). Our objective was to validate and assess the reliability of BICAMS to obtain normative data in Portuguese population.
Method: The sample composed of 107 MS patients and 62 healthy controls (HC). In order to test its reliability, BICAMS was re-administered in a subset of 25 patients after 3 month later. Depression, anxiety and fatigue were assessed by Hospital Anxiety and Depression Scale and Modified Fatigue Impact Scale (MFIS).
Results: The sample comprises a control group (n=62, age: M = 37,00; DP = 12,74, education:
M = 14,53; DP = 3,44) and a clinical group (n=107, age: M = 38,50; DP = 11,34, education: M = 13,51; DP = 3,82). About 64% of the participants were women. The groups did not differ for age, education,
or gender. The MS group performed significantly worse than the control group across the three neuropsychological tests, yielding the following values: SDMT: t(167) = 3.71, p = .000; CVLT-II: t(167) = 2.69, p = .008; and BVMT-R: t(167) = 2.33, p = .021. The mean raw scores for Portuguese normative data were as follows: SDMT: 58.18 ± 10.25; CVLT-II: 59.65 ± 10.96; and BVMT-R: 24.05 ± 6.47. Finally, test-retest reliability coefficients for each test were as follows: SDMT: r = .92; CVLT-II: r = .48; and BVMT-R: r = .86.
Conclusion: This BICAMS version is reliable and useful as a monitoring tool for identifying MS patients with cognitive impairment.
Disclosure:
Funding: This project was partially funded by a research grant from Bayer AG. The authors would like to thank Dr. Dawn Langdon for her advice and support during the course of this study.