Contributions
Abstract: EP1581
Type: ePoster
Abstract Category: Pathology and pathogenesis of MS - 24 Neuropsychology
Introduction: It has been postulated that 40% to 60% of people with multiple sclerosis (MS) have memory and learning problems. Training of executive functions has demonstrated to be effective for memory and learning rehabilitation (Mitolo, 2015).
Objectives: We aim to analyse differences between immediate recall and long term retrieval in patients with (MS) using Spanish Version of California Verbal Learning Test (TAVEC) and its relationship executive functioning (EF).
Method: 143 patients with remitting-relapsing MS (RRMS) were recruited from the clinic ( mean age: 42,39 y.o.) and a sample of 35 healthy controls (HC) of the same age and educational level. A complete neuropsychological assessment was administered to both groups. MS sample was classified in three groups: no cognitive impairment, mild cognitive impairment and moderate cognitive impairment. We analyse differences between immediate and delayed retrieval in TAVEC in the HC and MS and the relationship with verbal fluency as a measure of EF.
Results: All MS groups obtained significant better (p< 0.01) outcomes in long term retrieval than in short term retrieval; no significant differences were found in HC (p< 0.05). A positive correlation (p< 0.01) was found between phonological verbal fluency and memory in TAVEC for patients group.
Conclusions: MS patients obtain better delayed retrieval outcomes than in immediate memory. Verbal fluency is related to short and long term verbal memory in patients with multiple sclerosis and could explain the findings in TAVEC results . We suggest that patients with deficit in executive functioning take benefit of the semantic classification provided by this test what facilitates coding. Our results support previous research suggesting that EF are related to memory outcomes in patients with MS.
Disclosure: García-Vaz, F; Meca-Lallana, V; Palmi-Cortés, I; del Río Muñoz, B; Vivancos, J ; Martínez-Ginés, M.L; García-Domínguez, J.M; Cuello, J.P ; Romero-Delgado, F ; Higueras, Y . have received speaker honoraria and/or travel grants from Novartis, Biogen, Gencyme, Almirall, Bayer, Teva, Roche. A. . Rafael G. Gonzalez-Cuenca and Ariana Maldaña-Rivera has nothing to disclosure
Abstract: EP1581
Type: ePoster
Abstract Category: Pathology and pathogenesis of MS - 24 Neuropsychology
Introduction: It has been postulated that 40% to 60% of people with multiple sclerosis (MS) have memory and learning problems. Training of executive functions has demonstrated to be effective for memory and learning rehabilitation (Mitolo, 2015).
Objectives: We aim to analyse differences between immediate recall and long term retrieval in patients with (MS) using Spanish Version of California Verbal Learning Test (TAVEC) and its relationship executive functioning (EF).
Method: 143 patients with remitting-relapsing MS (RRMS) were recruited from the clinic ( mean age: 42,39 y.o.) and a sample of 35 healthy controls (HC) of the same age and educational level. A complete neuropsychological assessment was administered to both groups. MS sample was classified in three groups: no cognitive impairment, mild cognitive impairment and moderate cognitive impairment. We analyse differences between immediate and delayed retrieval in TAVEC in the HC and MS and the relationship with verbal fluency as a measure of EF.
Results: All MS groups obtained significant better (p< 0.01) outcomes in long term retrieval than in short term retrieval; no significant differences were found in HC (p< 0.05). A positive correlation (p< 0.01) was found between phonological verbal fluency and memory in TAVEC for patients group.
Conclusions: MS patients obtain better delayed retrieval outcomes than in immediate memory. Verbal fluency is related to short and long term verbal memory in patients with multiple sclerosis and could explain the findings in TAVEC results . We suggest that patients with deficit in executive functioning take benefit of the semantic classification provided by this test what facilitates coding. Our results support previous research suggesting that EF are related to memory outcomes in patients with MS.
Disclosure: García-Vaz, F; Meca-Lallana, V; Palmi-Cortés, I; del Río Muñoz, B; Vivancos, J ; Martínez-Ginés, M.L; García-Domínguez, J.M; Cuello, J.P ; Romero-Delgado, F ; Higueras, Y . have received speaker honoraria and/or travel grants from Novartis, Biogen, Gencyme, Almirall, Bayer, Teva, Roche. A. . Rafael G. Gonzalez-Cuenca and Ariana Maldaña-Rivera has nothing to disclosure