Contributions
Abstract: EP1578
Type: ePoster
Abstract Category: Pathology and pathogenesis of MS - 24 Neuropsychology
Background: Multiple Sclerosis (MS) patients, usually show cognitive and motor deficits. These deficits are regularly assessed separately, however recent studies have found an interaction when these tasks are performed simultaneously (Cognitive-Motor Interaction, CMI). The research in CMI allows a more ecological approach to the description of MS symptoms.
Objectives:
1) To compare performance in CMI between MS patients and healthy controls.
2) To analyze the relationship between CMI and clinical variables and cognitive impairment.
Methods: Forty patients with relapsing-remitting MS and 20 healthy controls were included. Patients age: 38.03 ± 11.26; education: 13.55 ± 2.74; Expanded disability status scale (EDSS): 2.02 ± 0.93; Disease evolution: 10.81 ± 11.19. Controls age: 34.00 ± 14.25; education: 14.92 ± 2.15
Outcome measures:
Clinical variables: EDSS; Fatigue Severity Scale; Beck's Depression Inventory II.
Cognitive variables: BICAMS Battery;
Dual tasks: Two cognitive -motor interaction tasks (walking while performing verbal fluency/counting). The measure of the difference between subject performance in the simple task and in the situation of dual task was obtained. It was quantity: time, number of steps and cognitive performance.
Results: No significant differences were found between patients and controls in age (p=.268) and education (p= .083). Significant differences were found between patients and controls in CMI, in the time (fluency: p=.027; counting: p=.038), the steps of the counting task (p=.029) and in the performance of both cognitive tasks (fluency: p= .040; counting: p=.001). Significant correlations were found between CMI time and disease evolution (p=.025), number of steps and physical disability (p=.042), and between fluency and fatigue (p=.026). No correlations were found between CMI and depression. There were no differences in CMI between patients with and without cognitive impairment.
Conclusions: Patients with MS show alterations in cognitive-motor tasks. Patients with more years of evolution, disability and fatigue evidence a worse performance.
Disclosure:
Eizaguirre M.B.: Nothing to disclose
Merino A.: Nothing to disclose
Yastremiz C.: Nothing to disclose
Cabral N.: Nothing to disclose
Silva B.: Nothing to disclose
Alonso R.: Nothing to disclose
Vanotti S.: Nothing to disclose
Garcea O.: Nothing to disclose
Abstract: EP1578
Type: ePoster
Abstract Category: Pathology and pathogenesis of MS - 24 Neuropsychology
Background: Multiple Sclerosis (MS) patients, usually show cognitive and motor deficits. These deficits are regularly assessed separately, however recent studies have found an interaction when these tasks are performed simultaneously (Cognitive-Motor Interaction, CMI). The research in CMI allows a more ecological approach to the description of MS symptoms.
Objectives:
1) To compare performance in CMI between MS patients and healthy controls.
2) To analyze the relationship between CMI and clinical variables and cognitive impairment.
Methods: Forty patients with relapsing-remitting MS and 20 healthy controls were included. Patients age: 38.03 ± 11.26; education: 13.55 ± 2.74; Expanded disability status scale (EDSS): 2.02 ± 0.93; Disease evolution: 10.81 ± 11.19. Controls age: 34.00 ± 14.25; education: 14.92 ± 2.15
Outcome measures:
Clinical variables: EDSS; Fatigue Severity Scale; Beck's Depression Inventory II.
Cognitive variables: BICAMS Battery;
Dual tasks: Two cognitive -motor interaction tasks (walking while performing verbal fluency/counting). The measure of the difference between subject performance in the simple task and in the situation of dual task was obtained. It was quantity: time, number of steps and cognitive performance.
Results: No significant differences were found between patients and controls in age (p=.268) and education (p= .083). Significant differences were found between patients and controls in CMI, in the time (fluency: p=.027; counting: p=.038), the steps of the counting task (p=.029) and in the performance of both cognitive tasks (fluency: p= .040; counting: p=.001). Significant correlations were found between CMI time and disease evolution (p=.025), number of steps and physical disability (p=.042), and between fluency and fatigue (p=.026). No correlations were found between CMI and depression. There were no differences in CMI between patients with and without cognitive impairment.
Conclusions: Patients with MS show alterations in cognitive-motor tasks. Patients with more years of evolution, disability and fatigue evidence a worse performance.
Disclosure:
Eizaguirre M.B.: Nothing to disclose
Merino A.: Nothing to disclose
Yastremiz C.: Nothing to disclose
Cabral N.: Nothing to disclose
Silva B.: Nothing to disclose
Alonso R.: Nothing to disclose
Vanotti S.: Nothing to disclose
Garcea O.: Nothing to disclose