Contributions
Abstract: EP1447
Type: ePoster
Abstract Category: Clinical aspects of MS - 11 Comorbidity
Background: Last years there is an emerging interest on metabolic and CV comorbidities in MS patients, especially on the association of these parameters with outcome and prognosis of MS. It's known that inflammation play a fundamental role in both conditions and maybe by treating MetS or modifying CV risk factors one can reduce the odds for disability and progression of MS.
Goals: This study aim to determine the frequency between CV risk factors, metabolic syndrome (according to the criteria of International Diabetes Federation) and MS.
Methods: 59 patients (42 males and 17 females, 25 to 60 year-old) with relapsing remitting MS (mean EDSS=3 and mean duration of disease 9 years) under disease modifying treatment were recorded for hypertension, smoking, dyslipidemia, obesity, type 2 diabetes and positive family history for CV disease. Body mass index (BMI), waist circumference and levels of fasting glucose, HDL, LDL cholesterol and triglycerides were also obtained.
Results: MetS was evaluated on 22.3% but half of our patients had at least two CV risk factors. Furthermore, abnormal BMI was frequently recorded (overweighed 32.20%, with obesity 16.9%), and 49% of our cohort admitted that they didn't do any gym or physical exercise. Smoking is a frequent habit among MS patients (47.2%) and regarding the family history it is positive for CV risk factors almost at half of them.
Conclusions: Metabolic and CV comorbidities in MS are not yet elucidated and future research should be elaborated in order to improve our understanding for the possible interaction in etiology, disability and prognosis of MS.
Disclosure:
Charisiou Kl.:Nothing to disclosure
Pelidou SH: Nothing to disclosure
Kyritsis AP: Nothing to disclosure
Abstract: EP1447
Type: ePoster
Abstract Category: Clinical aspects of MS - 11 Comorbidity
Background: Last years there is an emerging interest on metabolic and CV comorbidities in MS patients, especially on the association of these parameters with outcome and prognosis of MS. It's known that inflammation play a fundamental role in both conditions and maybe by treating MetS or modifying CV risk factors one can reduce the odds for disability and progression of MS.
Goals: This study aim to determine the frequency between CV risk factors, metabolic syndrome (according to the criteria of International Diabetes Federation) and MS.
Methods: 59 patients (42 males and 17 females, 25 to 60 year-old) with relapsing remitting MS (mean EDSS=3 and mean duration of disease 9 years) under disease modifying treatment were recorded for hypertension, smoking, dyslipidemia, obesity, type 2 diabetes and positive family history for CV disease. Body mass index (BMI), waist circumference and levels of fasting glucose, HDL, LDL cholesterol and triglycerides were also obtained.
Results: MetS was evaluated on 22.3% but half of our patients had at least two CV risk factors. Furthermore, abnormal BMI was frequently recorded (overweighed 32.20%, with obesity 16.9%), and 49% of our cohort admitted that they didn't do any gym or physical exercise. Smoking is a frequent habit among MS patients (47.2%) and regarding the family history it is positive for CV risk factors almost at half of them.
Conclusions: Metabolic and CV comorbidities in MS are not yet elucidated and future research should be elaborated in order to improve our understanding for the possible interaction in etiology, disability and prognosis of MS.
Disclosure:
Charisiou Kl.:Nothing to disclosure
Pelidou SH: Nothing to disclosure
Kyritsis AP: Nothing to disclosure