Contributions
Abstract: EP1350
Type: ePoster
Abstract Category: Clinical aspects of MS - 5 Epidemiology
Background: Neuromyelitys optica is a rare disease and epidemiological data on NMO is limited. The goal of this study was evaluation of demographic and clinical features of NMO in Caucasian population in Tehran, Iran.
Method: A cross sectional study among patients registered with NMO diagnosis was performed in Tehran during 2015 to 2016. We design a questionnaire to cover the epidemiological and clinical data of NMO in Tehran. Structured face to face interviews were conducted with 147 patients. The logistic regression was applied in analysis via software package SPSS.
Result: Among 147 patients, mean age was 36.09 years and 127 (86.4%) were female. Mean of disease onset age was 31.53 years. NMO-Ig G was positive in 71 (54.2%) patients and did not differ significantly between male and female (female positivity=56.3%, male positivity=42.1%; p-value=0.32). 42.2% of patients had primary presentation by transverse myelitis (TM) and optic neuritis (ON). In the next rank were patients presented only with TM (25.9%) or ON (18.4%). Totally 61 (46.6%) patients had a history of head trauma with 59 % NMO-Ig G positivity but it was not significantly higher than patients with no history of head trauma (p-value=0.38; OR= 1.44 (0.72-2.87).
Conclusions: NMO is higher among female and younger age. Most of NMO patients present with TM and ON. Sex and history of head trauma did not significantly influence NMO-Ig G positivity.
Disclosure:
Funding Source: This study was funded by Tehran University of medical sciences.
Conflict of Interest: Authors declare no conflict of interest The outcomes of this study examined some significant epidemiological factors and clinical features for NMO.
Abstract: EP1350
Type: ePoster
Abstract Category: Clinical aspects of MS - 5 Epidemiology
Background: Neuromyelitys optica is a rare disease and epidemiological data on NMO is limited. The goal of this study was evaluation of demographic and clinical features of NMO in Caucasian population in Tehran, Iran.
Method: A cross sectional study among patients registered with NMO diagnosis was performed in Tehran during 2015 to 2016. We design a questionnaire to cover the epidemiological and clinical data of NMO in Tehran. Structured face to face interviews were conducted with 147 patients. The logistic regression was applied in analysis via software package SPSS.
Result: Among 147 patients, mean age was 36.09 years and 127 (86.4%) were female. Mean of disease onset age was 31.53 years. NMO-Ig G was positive in 71 (54.2%) patients and did not differ significantly between male and female (female positivity=56.3%, male positivity=42.1%; p-value=0.32). 42.2% of patients had primary presentation by transverse myelitis (TM) and optic neuritis (ON). In the next rank were patients presented only with TM (25.9%) or ON (18.4%). Totally 61 (46.6%) patients had a history of head trauma with 59 % NMO-Ig G positivity but it was not significantly higher than patients with no history of head trauma (p-value=0.38; OR= 1.44 (0.72-2.87).
Conclusions: NMO is higher among female and younger age. Most of NMO patients present with TM and ON. Sex and history of head trauma did not significantly influence NMO-Ig G positivity.
Disclosure:
Funding Source: This study was funded by Tehran University of medical sciences.
Conflict of Interest: Authors declare no conflict of interest The outcomes of this study examined some significant epidemiological factors and clinical features for NMO.