Contributions
Abstract: EP1328
Type: ePoster
Abstract Category: Clinical aspects of MS - 4 Natural course
Introduction: In this study we tried to describe the clinical presentation of the patients with CIS in southern Iran and their follow up in 10 years.
Patients and method: 143 patients with CIS (124 females and 19 males) were enrolled in the study. Demographic data, clinical presentation and MRI findings of the patients were collected and patients were followed for 10 years.
Results: The most common initial clinical presentation was optic neuritis (40.6%). After a mean follow-up of 3.4 ±1.1 years, 38/143 patients (26.6%) had converted to CDMS.
The mean age at diagnosis was lower in CIS patients who converted to MS (27.6 versus 29.4 years), but it was not statistically significant (p=0.23).
The conversion rate to CDMS was 49.2% (30/61) for patients who had≥3 Brain MRI lesions, but it was 9.8% (8/72) in patients who had 3< lesions (OR =8.95, 95% CI=3.69-21.7, p< 0.001).
Conclusion: The conversion rate in this Iranian population was similar to Western countries. Also, this study confirms this concept that the number of MRI lesions at baseline can be used as strong predictors of CIS conversion to CDMS.
Keywords: Clinical Presentation, Iranian Population, Multiple Sclerosis, Clinically isolated syndrome
Disclosure: There is no Conflict of interest.
Abstract: EP1328
Type: ePoster
Abstract Category: Clinical aspects of MS - 4 Natural course
Introduction: In this study we tried to describe the clinical presentation of the patients with CIS in southern Iran and their follow up in 10 years.
Patients and method: 143 patients with CIS (124 females and 19 males) were enrolled in the study. Demographic data, clinical presentation and MRI findings of the patients were collected and patients were followed for 10 years.
Results: The most common initial clinical presentation was optic neuritis (40.6%). After a mean follow-up of 3.4 ±1.1 years, 38/143 patients (26.6%) had converted to CDMS.
The mean age at diagnosis was lower in CIS patients who converted to MS (27.6 versus 29.4 years), but it was not statistically significant (p=0.23).
The conversion rate to CDMS was 49.2% (30/61) for patients who had≥3 Brain MRI lesions, but it was 9.8% (8/72) in patients who had 3< lesions (OR =8.95, 95% CI=3.69-21.7, p< 0.001).
Conclusion: The conversion rate in this Iranian population was similar to Western countries. Also, this study confirms this concept that the number of MRI lesions at baseline can be used as strong predictors of CIS conversion to CDMS.
Keywords: Clinical Presentation, Iranian Population, Multiple Sclerosis, Clinically isolated syndrome
Disclosure: There is no Conflict of interest.