Contributions
Abstract: EP1320
Type: ePoster
Abstract Category: Clinical aspects of MS - 3 Paediatric MS
Introduction: Multiple sclerosis (MS) is a disease of young adults, but its onset in
Childhood is frequently observed. In recent years a number of Number of networks participated in advancing the management of this disease in the child.
Objectives: Describe the clinical, paraclinic characteristics of pediatric MS.
Appreciate the response to different treatments.
Describe the evolution and compare it to adult onset.
Patients and methods: Prospective and retrospective study of MS patients with baseline age less than 18 Years. The positive diagnosis was made according to McDonald´s criteria. Cerebral and spinal cord was performed with cerebrospinal fluid study.
Was appreciated by the EDSS. The substantive treatment was prescribed according to the clinical form.
Results: We collected 25 patients. The sex ratio (F / H) 3.3. Average starting range was
15 ± 4.38 years. The mono symptomaticonset was the most frequent (76.6%).cerebral MRI showed hypersignals peri ventricular (91%), cerebellum and corpus callosum (38% and 36%). Interferons were prescribed in 76%, Natalizumab in 9.5%. The reccurent-remitting form was observed in 87.5%. The current EDSS of patients is between 4-6 in 28.5% and greater than 6 In 19%. The median time to reach EDSS 6 in our patients was 8.27 -10.68 years where as in the adult form it was 12.17 - 13.24 years.
Conclusion: During childhood MS, functional and cognitive dysfunction
Interferes with academic achievement. Start treatment as early as possible
Could improve the quality of life of young patients.
Disclosure: No conflict of interest
Abstract: EP1320
Type: ePoster
Abstract Category: Clinical aspects of MS - 3 Paediatric MS
Introduction: Multiple sclerosis (MS) is a disease of young adults, but its onset in
Childhood is frequently observed. In recent years a number of Number of networks participated in advancing the management of this disease in the child.
Objectives: Describe the clinical, paraclinic characteristics of pediatric MS.
Appreciate the response to different treatments.
Describe the evolution and compare it to adult onset.
Patients and methods: Prospective and retrospective study of MS patients with baseline age less than 18 Years. The positive diagnosis was made according to McDonald´s criteria. Cerebral and spinal cord was performed with cerebrospinal fluid study.
Was appreciated by the EDSS. The substantive treatment was prescribed according to the clinical form.
Results: We collected 25 patients. The sex ratio (F / H) 3.3. Average starting range was
15 ± 4.38 years. The mono symptomaticonset was the most frequent (76.6%).cerebral MRI showed hypersignals peri ventricular (91%), cerebellum and corpus callosum (38% and 36%). Interferons were prescribed in 76%, Natalizumab in 9.5%. The reccurent-remitting form was observed in 87.5%. The current EDSS of patients is between 4-6 in 28.5% and greater than 6 In 19%. The median time to reach EDSS 6 in our patients was 8.27 -10.68 years where as in the adult form it was 12.17 - 13.24 years.
Conclusion: During childhood MS, functional and cognitive dysfunction
Interferes with academic achievement. Start treatment as early as possible
Could improve the quality of life of young patients.
Disclosure: No conflict of interest