Contributions
Abstract: EP1308
Type: ePoster
Abstract Category: Clinical aspects of MS - 3 Paediatric MS
Introduction: Childhood multiple sclerosis (early-onset multiple sclerosis) approximately incorporates 3-5% of the MS population. In this study we tried to investigate prevalence, incidence and epidemiological aspects of childhood MS in last decade in Fars, southern Iran.
Patients and methods: During a retrospective study between 2005 to 2016 all patients with childhood MS (onset before age 16) were in enrolled in the study. Prevalence, Incidence, demographic data, primary clinical presentation and month of birth of all patients were collected via a data gathering form. Statistical analysis was performed under supervision of statistical specialist.
Results: In this duration overall 209 patients with childhood MS were diagnosed. Prevalence of Childhood MS was 4/24(Per 100.000) and mean incidence in this duration was 0.85 (Per 100.000 in each year). The incidence rate increased significantly from 2005 to 2016 (P value < 0.01).
13.4% (28 Patients) were boys. Mean age of the patients at the time of diagnosis was 14.02 years
(± 2.8) (Range: 1 to 16 years). Mean age of diagnosis in boys was 12.64 ± 4.24 and in girls was
14.24 ± 2.45 years. The difference between the age of diagnosis in girls and boys was statistically significant. (P value: 0.005) Only 6% of patients had < 10 years in the time of diagnosis. Optic Neuritis was the most common initial presentation in our patients. (37%).
Discussion: Here we showed that Childhood MS in Iran is not a rare condition especially in the girls and the incidence rate increased recently. Nowadays, Prevalence is similar to the western countries. Clinical suspicious is very important for correct and early diagnosis.
Keywords: Childhood MS, Iran, Epidemiology
Disclosure: There is no conflict of interest .
Abstract: EP1308
Type: ePoster
Abstract Category: Clinical aspects of MS - 3 Paediatric MS
Introduction: Childhood multiple sclerosis (early-onset multiple sclerosis) approximately incorporates 3-5% of the MS population. In this study we tried to investigate prevalence, incidence and epidemiological aspects of childhood MS in last decade in Fars, southern Iran.
Patients and methods: During a retrospective study between 2005 to 2016 all patients with childhood MS (onset before age 16) were in enrolled in the study. Prevalence, Incidence, demographic data, primary clinical presentation and month of birth of all patients were collected via a data gathering form. Statistical analysis was performed under supervision of statistical specialist.
Results: In this duration overall 209 patients with childhood MS were diagnosed. Prevalence of Childhood MS was 4/24(Per 100.000) and mean incidence in this duration was 0.85 (Per 100.000 in each year). The incidence rate increased significantly from 2005 to 2016 (P value < 0.01).
13.4% (28 Patients) were boys. Mean age of the patients at the time of diagnosis was 14.02 years
(± 2.8) (Range: 1 to 16 years). Mean age of diagnosis in boys was 12.64 ± 4.24 and in girls was
14.24 ± 2.45 years. The difference between the age of diagnosis in girls and boys was statistically significant. (P value: 0.005) Only 6% of patients had < 10 years in the time of diagnosis. Optic Neuritis was the most common initial presentation in our patients. (37%).
Discussion: Here we showed that Childhood MS in Iran is not a rare condition especially in the girls and the incidence rate increased recently. Nowadays, Prevalence is similar to the western countries. Clinical suspicious is very important for correct and early diagnosis.
Keywords: Childhood MS, Iran, Epidemiology
Disclosure: There is no conflict of interest .