Contributions
Abstract: EP1291
Type: ePoster
Abstract Category: Clinical aspects of MS - 1 Diagnosis and differential diagnosis
Background and objective: The most frequent cause of visual loss in young adults is optic neuritis, whose pathogenesis is usually inflammatory and demyelinating. Up to 75% of the cases will meet multiple sclerosis (MS) criteria in 15 years. But there are other pathologies that can mimic optic neuritis and should be included in the diferencial diagnosis. We report two cases of optic neuritis, uncommon in the literature, and to be taken into account in the differential diagnosis of MS.
Method: Case report of a 14-year-old man with a optic neuritis 2ª to drusen and a case report of a 41-year-old man with a optic neuropathy caused by antibody anti recoverina.
Results: We report a case of a 14-year-old man who goes to the emergency room for a blurred vision of the left eye, eminently in the lower field, without added pain. He was seen by the ophthalmology service, that warn pseudo edema papila, advising assessment by the neurology service and review by them the next day. That day, they noticed splinter hemorrhages around the papilla motive for which they entered the neurology service. Brain CT, OCT and ultrasound were obtained, which evidenced papilla drusen. Diagnosis of non-arteritic ischemic optic neuritis secondary to drusen was issued. A 47-year-old man who visited the neurology service due to episodes of vision of spots in the right eye and double vision, lasting minutes, that were repeated 2 to 3 times a month. As personal background he referred Hodgkin´s disease, treated with bone marrow transplantation 10 years earlier. No abnormalities in the review by the ophthalmology service. Brain MRI with peri-ventricular demyelinating lesions, negative oligoclonal bands, pathological evoked potentials, and anti-recoverine positive body. He was diagnosed of paraneoplastic syndrome.
Conclusions: Although multiple sclerosis is a relatively frequent disease in young people with optic neuritis, other diseases have to be considered in the differential diagnosis of these diseases. It is necessary to recognize those atypical forms of optic neuritis in which the aetiological study must be extended. Important advances have been made in the knowledge of some of them thanks to the determination of specific markers.
Disclosure: nothing to disclose
Abstract: EP1291
Type: ePoster
Abstract Category: Clinical aspects of MS - 1 Diagnosis and differential diagnosis
Background and objective: The most frequent cause of visual loss in young adults is optic neuritis, whose pathogenesis is usually inflammatory and demyelinating. Up to 75% of the cases will meet multiple sclerosis (MS) criteria in 15 years. But there are other pathologies that can mimic optic neuritis and should be included in the diferencial diagnosis. We report two cases of optic neuritis, uncommon in the literature, and to be taken into account in the differential diagnosis of MS.
Method: Case report of a 14-year-old man with a optic neuritis 2ª to drusen and a case report of a 41-year-old man with a optic neuropathy caused by antibody anti recoverina.
Results: We report a case of a 14-year-old man who goes to the emergency room for a blurred vision of the left eye, eminently in the lower field, without added pain. He was seen by the ophthalmology service, that warn pseudo edema papila, advising assessment by the neurology service and review by them the next day. That day, they noticed splinter hemorrhages around the papilla motive for which they entered the neurology service. Brain CT, OCT and ultrasound were obtained, which evidenced papilla drusen. Diagnosis of non-arteritic ischemic optic neuritis secondary to drusen was issued. A 47-year-old man who visited the neurology service due to episodes of vision of spots in the right eye and double vision, lasting minutes, that were repeated 2 to 3 times a month. As personal background he referred Hodgkin´s disease, treated with bone marrow transplantation 10 years earlier. No abnormalities in the review by the ophthalmology service. Brain MRI with peri-ventricular demyelinating lesions, negative oligoclonal bands, pathological evoked potentials, and anti-recoverine positive body. He was diagnosed of paraneoplastic syndrome.
Conclusions: Although multiple sclerosis is a relatively frequent disease in young people with optic neuritis, other diseases have to be considered in the differential diagnosis of these diseases. It is necessary to recognize those atypical forms of optic neuritis in which the aetiological study must be extended. Important advances have been made in the knowledge of some of them thanks to the determination of specific markers.
Disclosure: nothing to disclose