Contributions
Abstract: P905
Type: Poster
Abstract Category: Clinical aspects of MS - Clinical assessment tools
Background: NMO and Neuromyelitis optica spectrum disorders (NMOSD) are uncommon neuro-inflammatory syndrome disorders with specific physiopathology and clinical course. The symptoms and presentations are still being explored and not well stablished or described.
Objective: To describe unpublished common clinical features in NMO and NMOSD and evaluate the prevalence of this symptoms in our sample.
Method: Clinical evaluation of 22 patients from a neuroimunology specialized ambulatory with diagnosis of NMO ans NMOSD.
Result: In our sample, 87% (19) of the patients were female, with a mean age of 40 (19 - 59) y.o. The mean disease duration time was of 68 (1 - 244) months , with a mean delay of 23 (1 - 44)months from the initial symptoms to the disease diagnosis. Regarding anti-aquaporin antibodies 87% (19) were seropositive and 13% (3) negative. 50% had neuritis as initial presentation, followed by 30% with myelitis and 20% with are postrema radiologial envolvement and clinical symptoms. Considering all the disease presentation time, 80% had neuritis, 70% had myelitis and 30% had area postrema symptoms and 60% reported disautonomic symptoms. Among the 82% (18) patients with medullary involvement, 100% had painful tonic spasms, 67% (12) reported a compressive chest or abdominal pain, 44%(8) had lhermite signal. Moreover, 61%(11) reported urinary incontinence and 61% (11) unresponsive neuropathic pain. Regarding the patients with neuritis, 57% (11) had continous eye pain. Pruridous was also a complain of 36% (8) of all the patients.
Conclusion: Our results showed an important delay from the symptoms onset to the diagnosis. Therefore is importante to describe the most prevalente symptons as compressive chest or abdominal pain and continuos eye pain that may facilitate the diagnosis of the NMO and NMOSD. Since these features are not described in other diseases and might increase the sensibility for the disease investigation.
Disclosure: nothing to disclose
Abstract: P905
Type: Poster
Abstract Category: Clinical aspects of MS - Clinical assessment tools
Background: NMO and Neuromyelitis optica spectrum disorders (NMOSD) are uncommon neuro-inflammatory syndrome disorders with specific physiopathology and clinical course. The symptoms and presentations are still being explored and not well stablished or described.
Objective: To describe unpublished common clinical features in NMO and NMOSD and evaluate the prevalence of this symptoms in our sample.
Method: Clinical evaluation of 22 patients from a neuroimunology specialized ambulatory with diagnosis of NMO ans NMOSD.
Result: In our sample, 87% (19) of the patients were female, with a mean age of 40 (19 - 59) y.o. The mean disease duration time was of 68 (1 - 244) months , with a mean delay of 23 (1 - 44)months from the initial symptoms to the disease diagnosis. Regarding anti-aquaporin antibodies 87% (19) were seropositive and 13% (3) negative. 50% had neuritis as initial presentation, followed by 30% with myelitis and 20% with are postrema radiologial envolvement and clinical symptoms. Considering all the disease presentation time, 80% had neuritis, 70% had myelitis and 30% had area postrema symptoms and 60% reported disautonomic symptoms. Among the 82% (18) patients with medullary involvement, 100% had painful tonic spasms, 67% (12) reported a compressive chest or abdominal pain, 44%(8) had lhermite signal. Moreover, 61%(11) reported urinary incontinence and 61% (11) unresponsive neuropathic pain. Regarding the patients with neuritis, 57% (11) had continous eye pain. Pruridous was also a complain of 36% (8) of all the patients.
Conclusion: Our results showed an important delay from the symptoms onset to the diagnosis. Therefore is importante to describe the most prevalente symptons as compressive chest or abdominal pain and continuos eye pain that may facilitate the diagnosis of the NMO and NMOSD. Since these features are not described in other diseases and might increase the sensibility for the disease investigation.
Disclosure: nothing to disclose