Contributions
Abstract: P854
Type: Poster
Abstract Category: Clinical aspects of MS - Epidemiology
Introduction: Data regarding the rates of pregnancy in women with multiple sclerosis (MS) over time are lacking. The objective of this study was to evaluate the rate of pregnancy in women with MS from 2006 to 2014, and to determine how these trends varied with age, region, and payer type.
Methods: A retrospective analysis of women with MS (International Classification of Diseases, Ninth Revision, Clinical Modification code: 340.xx) from IMS Health Real World Data Adjudicated Claims - US data was conducted. The trends in pregnancy rates were assessed by year (2006-2014), age, region, and payer type. Baseline demographic and clinical characteristics were evaluated for women with MS with and without a pregnancy-related claim (diagnosis code or procedure) in the dataset for each year of available data.
Results: The number of women with MS included in the annual study cohorts from 2006 to 2014 ranged from 39,801 to 59,622. The average age of women with MS and a pregnancy-related claim ranged from 32.23 to 32.95 years, whereas the mean age of all women with MS ranged from 45.33 to 46.58 years. The proportion of women with MS and a pregnancy-related claim fluctuated between 2.40% and 2.55% between 2006 and 2011, declined to 2.48% in 2012, and increased to 2.57% in 2014. The proportion of women with MS with a pregnancy-related claim was highest for those aged 25-29 years (range: 11.64-13.62%) and 30-34 years (9.66-11.77%), those living in the Northeast (2.41-2.79%), and those with Medicaid health insurance (2.64-6.76%).
Conclusions: This study demonstrated there was a numerical increase in pregnancy rates in this US population of women with MS from 2006 to 2014. This is in contrast to pregnancy rates for all women in the US, which have steadily declined since 1990. More women with MS in the Northeast, aged 25-29 and 30-34 years, and with Medicaid health insurance had a pregnancy-related claim. This may reflect a change in perceptions regarding pregnancy risks in this patient population.
Disclosure: Maria K Houtchens received grant support from EMD Serono, Inc.
Natalie C Edwards is an employee of Health Services Consulting Corporation. Health Services Consulting Corporation received funding from EMD Serono, Inc., to run the analysis.
Kevin Stern is an employee of Boston Health Economics, Inc. (BHE). BHE received consulting fees from EMD Serono, Inc.
Amy L Phillips is an employee of EMD Serono, Inc., Rockland, MA, USA (a business of Merck KGaA, Darmstadt, Germany).
Abstract: P854
Type: Poster
Abstract Category: Clinical aspects of MS - Epidemiology
Introduction: Data regarding the rates of pregnancy in women with multiple sclerosis (MS) over time are lacking. The objective of this study was to evaluate the rate of pregnancy in women with MS from 2006 to 2014, and to determine how these trends varied with age, region, and payer type.
Methods: A retrospective analysis of women with MS (International Classification of Diseases, Ninth Revision, Clinical Modification code: 340.xx) from IMS Health Real World Data Adjudicated Claims - US data was conducted. The trends in pregnancy rates were assessed by year (2006-2014), age, region, and payer type. Baseline demographic and clinical characteristics were evaluated for women with MS with and without a pregnancy-related claim (diagnosis code or procedure) in the dataset for each year of available data.
Results: The number of women with MS included in the annual study cohorts from 2006 to 2014 ranged from 39,801 to 59,622. The average age of women with MS and a pregnancy-related claim ranged from 32.23 to 32.95 years, whereas the mean age of all women with MS ranged from 45.33 to 46.58 years. The proportion of women with MS and a pregnancy-related claim fluctuated between 2.40% and 2.55% between 2006 and 2011, declined to 2.48% in 2012, and increased to 2.57% in 2014. The proportion of women with MS with a pregnancy-related claim was highest for those aged 25-29 years (range: 11.64-13.62%) and 30-34 years (9.66-11.77%), those living in the Northeast (2.41-2.79%), and those with Medicaid health insurance (2.64-6.76%).
Conclusions: This study demonstrated there was a numerical increase in pregnancy rates in this US population of women with MS from 2006 to 2014. This is in contrast to pregnancy rates for all women in the US, which have steadily declined since 1990. More women with MS in the Northeast, aged 25-29 and 30-34 years, and with Medicaid health insurance had a pregnancy-related claim. This may reflect a change in perceptions regarding pregnancy risks in this patient population.
Disclosure: Maria K Houtchens received grant support from EMD Serono, Inc.
Natalie C Edwards is an employee of Health Services Consulting Corporation. Health Services Consulting Corporation received funding from EMD Serono, Inc., to run the analysis.
Kevin Stern is an employee of Boston Health Economics, Inc. (BHE). BHE received consulting fees from EMD Serono, Inc.
Amy L Phillips is an employee of EMD Serono, Inc., Rockland, MA, USA (a business of Merck KGaA, Darmstadt, Germany).