Contributions
Abstract: P789
Type: Poster
Abstract Category: RIMS - Neuropsychology and fatigue management
Objective: To study associations between dimensions of physical behavior and dimensions of fatigue in persons with multiple sclerosis (MS) related fatigue.
Design: cross-sectional analysis.
Setting: Outpatient rehabilitation departments. Physical behavior monitoring was conducted in participants´ daily environment.
Method:
Participants: 212 persons with MS from a multicenter RCT study. Persons with MS were severely fatigued, Fatigue Severity Scale median: 5.4 (4.8-5.9), and minimally to moderately neurological impaired, Expanded Disability Status Scale: 2.5 (2.0-3.5), 73.1% had Relapsing Remitting MS.
Interventions: not applicable.
Main Outcome Measures: Physical behavior was measured using an accelerometer and fatigue was measured by questionnaires (i.e., Checklist Individual Strength, Modified Fatigue Impact Scale). Fatigue questionnaires subscales and physical behavior outcomes were standardized and categorized in dimensions. For fatigue: subjective, physical, cognitive and psychological fatigue; for physical behavior:
activity amount, activity intensity, day pattern and distribution of activities.
Results: Physical behavior dimensions were significantly associated with only the physical fatigue dimension (omnibus F-test: 3.96, df1 = 4, df2 = 207, p = .004). Additional analysis showed that activity amount (B= -0.16, 95% CI = -0.27 to -0.04, p = .007), activity intensity (B= -0.18, 95% CI= -0.31 to -0.06, p= .004) and day pattern (B= -0.17, 95% CI = -0.28 to -0.06, p = .002) were the physical behavior dimensions that were significantly associated with physical fatigue. Age and gender did not confound these associations.
Conclusions: Physical behavior is weakly associated with physical fatigue and not with other fatigue dimensions, such as cognitive and psychological. This supports the notion that fatigue is multidimensional, and may imply that different treatment modalities should be considered in the treatment of fatigue.
Disclosure: Study is funded by Fonds NutsOhra and ZonMw
L.J.M Blikman: nothing to disclose
J. van Meeteren: nothing to disclose
D. Rizopoulos: nothing to disclose,
V. de Groot: nothing to disclose,
H. Beckerman: nothing to disclose,
H.J. Stam: nothing to disclose,
J.B.J. Bussmann: nothing to disclose
Abstract: P789
Type: Poster
Abstract Category: RIMS - Neuropsychology and fatigue management
Objective: To study associations between dimensions of physical behavior and dimensions of fatigue in persons with multiple sclerosis (MS) related fatigue.
Design: cross-sectional analysis.
Setting: Outpatient rehabilitation departments. Physical behavior monitoring was conducted in participants´ daily environment.
Method:
Participants: 212 persons with MS from a multicenter RCT study. Persons with MS were severely fatigued, Fatigue Severity Scale median: 5.4 (4.8-5.9), and minimally to moderately neurological impaired, Expanded Disability Status Scale: 2.5 (2.0-3.5), 73.1% had Relapsing Remitting MS.
Interventions: not applicable.
Main Outcome Measures: Physical behavior was measured using an accelerometer and fatigue was measured by questionnaires (i.e., Checklist Individual Strength, Modified Fatigue Impact Scale). Fatigue questionnaires subscales and physical behavior outcomes were standardized and categorized in dimensions. For fatigue: subjective, physical, cognitive and psychological fatigue; for physical behavior:
activity amount, activity intensity, day pattern and distribution of activities.
Results: Physical behavior dimensions were significantly associated with only the physical fatigue dimension (omnibus F-test: 3.96, df1 = 4, df2 = 207, p = .004). Additional analysis showed that activity amount (B= -0.16, 95% CI = -0.27 to -0.04, p = .007), activity intensity (B= -0.18, 95% CI= -0.31 to -0.06, p= .004) and day pattern (B= -0.17, 95% CI = -0.28 to -0.06, p = .002) were the physical behavior dimensions that were significantly associated with physical fatigue. Age and gender did not confound these associations.
Conclusions: Physical behavior is weakly associated with physical fatigue and not with other fatigue dimensions, such as cognitive and psychological. This supports the notion that fatigue is multidimensional, and may imply that different treatment modalities should be considered in the treatment of fatigue.
Disclosure: Study is funded by Fonds NutsOhra and ZonMw
L.J.M Blikman: nothing to disclose
J. van Meeteren: nothing to disclose
D. Rizopoulos: nothing to disclose,
V. de Groot: nothing to disclose,
H. Beckerman: nothing to disclose,
H.J. Stam: nothing to disclose,
J.B.J. Bussmann: nothing to disclose