Contributions
Abstract: P273
Type: Poster
Abstract Category: Clinical aspects of MS - MS Variants
Background and objective: With increasing availability of magnetic resonance imaging (MRI), there is also an increase in incidental abnormal findings suggestive of multiple sclerosis in people without multiple sclerosis symptoms and with normal neurological findings.These cases are classified as radiologically isolated syndrome (RIS).and the prevalence of RIS is not certain.The aim of this study was to determine the prevalence of RIS in two tertiary centers in a region with a high prevalence for MS.
Method: This is a retrospective cohort study conducted in 2016. All brain MRI examinations performed at two tertiary centers refered by a a neurologist for various complaints i.e. headache, dizziness, vertigo and other nospesific symptoms, none suggestive of a demyelinating process. A total of 2417 patients were included and analysed in the Neurology departments of these two centers. Age range was 18-65 and only 4 patients wih RIS were identified which is equivalent to 0.16%.Only two patient with RIS developed symptoms consistent with MS within 3 months, accompanied with radiological progression and was diagnosed as MS.
Conclusions: Although RIS, according to present criteria, is an ascertined as an uncommon finding, our results revealed that it is not that uncommon as previously reported.Larger multicenter studies are needed in order to study the prognosis of RIS and rate of conversion to MS.
Disclosure:
M.F. Oztekin: nothing to disclose
N. Oztekin: nothing to disclose
S.Bilen: nothing to disclose
F.Ak: nothing to disclose
Abstract: P273
Type: Poster
Abstract Category: Clinical aspects of MS - MS Variants
Background and objective: With increasing availability of magnetic resonance imaging (MRI), there is also an increase in incidental abnormal findings suggestive of multiple sclerosis in people without multiple sclerosis symptoms and with normal neurological findings.These cases are classified as radiologically isolated syndrome (RIS).and the prevalence of RIS is not certain.The aim of this study was to determine the prevalence of RIS in two tertiary centers in a region with a high prevalence for MS.
Method: This is a retrospective cohort study conducted in 2016. All brain MRI examinations performed at two tertiary centers refered by a a neurologist for various complaints i.e. headache, dizziness, vertigo and other nospesific symptoms, none suggestive of a demyelinating process. A total of 2417 patients were included and analysed in the Neurology departments of these two centers. Age range was 18-65 and only 4 patients wih RIS were identified which is equivalent to 0.16%.Only two patient with RIS developed symptoms consistent with MS within 3 months, accompanied with radiological progression and was diagnosed as MS.
Conclusions: Although RIS, according to present criteria, is an ascertined as an uncommon finding, our results revealed that it is not that uncommon as previously reported.Larger multicenter studies are needed in order to study the prognosis of RIS and rate of conversion to MS.
Disclosure:
M.F. Oztekin: nothing to disclose
N. Oztekin: nothing to disclose
S.Bilen: nothing to disclose
F.Ak: nothing to disclose