Contributions
Abstract: P1667
Type: LB Poster
Abstract Category: Late Breaking News
Background: Emotion recognition in patients with multiple sclerosis (MS) has been increasingly recognized. Most of these studies lacked a detailed correlation to clinical parameters and the impact of impaired emotion recognition on quality of life in patients with MS is unknown.
Here, we investigated whether emotion recognition in MS patients depends on depression, fatigue and cognition, and whether emotion recognition deficits lead to an impaired quality of life.
Methods: Individual cognition (assessed with Rao´s Brief repeatable battery, BRB), fatigue (fatigue scale for motor and cognitive function, FSMC), depression (Beck"s depression inventory, BDI) and clinical ability (expanded disability status scale, EDSS) were assessed from 50 patients prior to the emotion recognition test. In addition, a read the mind in the eyes test (RMIE) was performed, and percentage of correct responses and reaction times were scored. Furthermore, the quality of life was documented with the Multiple Sclerosis International Questionnaire of Quality of Life (MusiQOL).
Results: The average correct response on the RMIE was 64%, the average reaction time 9770ms. On a multiple regression analysis, emotion recognition ability was not explained by BRB (beta=0.13; p=0.4), FSMC (beta=0.06; p=0.7), BDI (beta=0.24; p=0.1) and EDSS (beta=-0.26; p=0.1; multiple regression R²=0.16; p=0.1).
Out of the MusiQOL total score and different subscores, only the subscore of the relationship to friends (RFr) was correlating to the mean reaction time of the RMIE. When testing the impact of the other variables (BRB, FSMC, BDI, EDSS) as well as the RMIE reaction time on the RFr, only RMIE reaction time correlated significantly (beta -0.29; p=0.04).
Discussion: Our data demonstrated that emotion recognition ability can be impaired in MS patients independent of other neuropsychological deficits. We also report that impairment in emotion recognition influences the ability to communicate properly, leading to an impaired relationship to friends in MS patients.
Disclosure:
M. Grothe has received research grants and travel support from TEVA pharma and Novartis.
A. Lischke has nothing to disclose.
M. Domin has nothing to disclose.
A. Dressel has received research grants, travel support and honoraria from Bayer, Biogen Idec, Genzyme, Merck Serono, Novartis and Teva Pharma.
Abstract: P1667
Type: LB Poster
Abstract Category: Late Breaking News
Background: Emotion recognition in patients with multiple sclerosis (MS) has been increasingly recognized. Most of these studies lacked a detailed correlation to clinical parameters and the impact of impaired emotion recognition on quality of life in patients with MS is unknown.
Here, we investigated whether emotion recognition in MS patients depends on depression, fatigue and cognition, and whether emotion recognition deficits lead to an impaired quality of life.
Methods: Individual cognition (assessed with Rao´s Brief repeatable battery, BRB), fatigue (fatigue scale for motor and cognitive function, FSMC), depression (Beck"s depression inventory, BDI) and clinical ability (expanded disability status scale, EDSS) were assessed from 50 patients prior to the emotion recognition test. In addition, a read the mind in the eyes test (RMIE) was performed, and percentage of correct responses and reaction times were scored. Furthermore, the quality of life was documented with the Multiple Sclerosis International Questionnaire of Quality of Life (MusiQOL).
Results: The average correct response on the RMIE was 64%, the average reaction time 9770ms. On a multiple regression analysis, emotion recognition ability was not explained by BRB (beta=0.13; p=0.4), FSMC (beta=0.06; p=0.7), BDI (beta=0.24; p=0.1) and EDSS (beta=-0.26; p=0.1; multiple regression R²=0.16; p=0.1).
Out of the MusiQOL total score and different subscores, only the subscore of the relationship to friends (RFr) was correlating to the mean reaction time of the RMIE. When testing the impact of the other variables (BRB, FSMC, BDI, EDSS) as well as the RMIE reaction time on the RFr, only RMIE reaction time correlated significantly (beta -0.29; p=0.04).
Discussion: Our data demonstrated that emotion recognition ability can be impaired in MS patients independent of other neuropsychological deficits. We also report that impairment in emotion recognition influences the ability to communicate properly, leading to an impaired relationship to friends in MS patients.
Disclosure:
M. Grothe has received research grants and travel support from TEVA pharma and Novartis.
A. Lischke has nothing to disclose.
M. Domin has nothing to disclose.
A. Dressel has received research grants, travel support and honoraria from Bayer, Biogen Idec, Genzyme, Merck Serono, Novartis and Teva Pharma.