Contributions
Abstract: P1636
Type: LB Poster
Abstract Category: Late Breaking News
Objective: Swallowing mechanism and neurogenic dysphagia in multiple sclerosis (MS) have been rarely studied by electrophysiological methods. This study aims to evaluate the spontaneous swallowing and swallowing abnormalities in MS patients using by polygraphic electroencephalogram (EEG) recording methods.
Material and method: A prospective study of 49 patients with relapsing remitting MS and 19 age-matched healthy adults was investigated. Clinical evaluation and degree of of dysphagia were performed with a dysphagia grading scale. All patients were thoroughly questioned with respect to dysphagia and aspiration along with a neurological examination of their face, tongue, mouth, pharynx, and larynx. We used a polygraphic EEG recording to measure spontaneous swallowing in 1 hour polygraphic recording in patients with MS. The vertical movements of the larynx during swallowing were recorded by a laryngeal sensor. Cardiac rhythm, respiration and sympathetic skin responses were synchronously recorded during swallowing as well.
Results: Clinical dysphagia was found in 20 % of MS patients, while electrophysiological swallowing abnormalities were encountered in 67.3 % of patients. No healthy adults had clinical or subclinical dysphagia. There were significant differences in rate of swallowing in awake (p: 0,006), rate of trigger swallowing in awake (p: 0,027), double swallowing (p: 0,005), triple swallowing (p: 0,001), double plus triple swallowing (p: 0,002) salvo type swallowing (p: 0,024) between MS patients and control group. The rate of all salvo type swallowing was more frequent in MS patients with clinical dysphagia when compared to nondysphagic MS patients [salvo type 5 ( p:0,012), salvo type 6 (p: 0,038), salvo type 7 (p:0,038), salvo type 8 (p: 0,038) and double plus triple swallowing (p: 0,044)]
Conclusion: This is the first study investigating swallowing abnormalities and subclinical dysphagia with polygraphic methods. in MS patients with mild disability. The electrophysio-logical tests described in this study are useful to uncover subclinical dysphagia since they have the advantage of being rapid, easy to apply, non-invasive, and without risk for the patients.
Disclosure:
Yesim Beckmann: nothing to disclose
Hülya Erkoyun: nothing to disclose
Tülay Kurt İncesu: nothing to disclose
Sevgin Gökçe: nothing to disclose
Cumhur Ertekin: nothing to disclose
Abstract: P1636
Type: LB Poster
Abstract Category: Late Breaking News
Objective: Swallowing mechanism and neurogenic dysphagia in multiple sclerosis (MS) have been rarely studied by electrophysiological methods. This study aims to evaluate the spontaneous swallowing and swallowing abnormalities in MS patients using by polygraphic electroencephalogram (EEG) recording methods.
Material and method: A prospective study of 49 patients with relapsing remitting MS and 19 age-matched healthy adults was investigated. Clinical evaluation and degree of of dysphagia were performed with a dysphagia grading scale. All patients were thoroughly questioned with respect to dysphagia and aspiration along with a neurological examination of their face, tongue, mouth, pharynx, and larynx. We used a polygraphic EEG recording to measure spontaneous swallowing in 1 hour polygraphic recording in patients with MS. The vertical movements of the larynx during swallowing were recorded by a laryngeal sensor. Cardiac rhythm, respiration and sympathetic skin responses were synchronously recorded during swallowing as well.
Results: Clinical dysphagia was found in 20 % of MS patients, while electrophysiological swallowing abnormalities were encountered in 67.3 % of patients. No healthy adults had clinical or subclinical dysphagia. There were significant differences in rate of swallowing in awake (p: 0,006), rate of trigger swallowing in awake (p: 0,027), double swallowing (p: 0,005), triple swallowing (p: 0,001), double plus triple swallowing (p: 0,002) salvo type swallowing (p: 0,024) between MS patients and control group. The rate of all salvo type swallowing was more frequent in MS patients with clinical dysphagia when compared to nondysphagic MS patients [salvo type 5 ( p:0,012), salvo type 6 (p: 0,038), salvo type 7 (p:0,038), salvo type 8 (p: 0,038) and double plus triple swallowing (p: 0,044)]
Conclusion: This is the first study investigating swallowing abnormalities and subclinical dysphagia with polygraphic methods. in MS patients with mild disability. The electrophysio-logical tests described in this study are useful to uncover subclinical dysphagia since they have the advantage of being rapid, easy to apply, non-invasive, and without risk for the patients.
Disclosure:
Yesim Beckmann: nothing to disclose
Hülya Erkoyun: nothing to disclose
Tülay Kurt İncesu: nothing to disclose
Sevgin Gökçe: nothing to disclose
Cumhur Ertekin: nothing to disclose