ECTRIMS eLearning

Objectively measured physical activity and sedentary behaviour profiles of people moderately affected by Multiple Sclerosis
Author(s): ,
E.H Coulter
Affiliations:
University of Glasgow, Glasgow
,
J Freeman
Affiliations:
Plymouth University, Plymouth
,
L Miller
Affiliations:
NHS Ayrshire & Arran, Irvine
,
B Weller
Affiliations:
University of Edinburgh, Edinburgh, United Kingdom
,
A Mcconnachie
Affiliations:
University of Glasgow, Glasgow
,
P.G Mattiosn
Affiliations:
NHS Ayrshire & Arran, Irvine
,
O Wu
Affiliations:
University of Glasgow, Glasgow
L Paul
Affiliations:
University of Glasgow, Glasgow
ECTRIMS Learn. Coulter E. 09/16/16; 146012; P1331
Elaine H. Coulter
Elaine H. Coulter
Contributions
Abstract

Abstract: P1331

Type: Poster

Abstract Category: RIMS - Exercise

Introduction: Remaining physically active is important to maintain functional ability, independence, quality of life and reducing the incidence of co-morbid disease. People with Multiple Sclerosis (MS) may find it difficult to engage in Physical Activity (PA). Previous research in MS has focussed on PA in MS however sedentary behaviour (SB) is associated with increased cardiovascular risk in healthy and other clinical populations.

Objective: To assess the PA and SB profiles of people moderately affected by MS with respect to disability level.

Methods: Data is reported for eighty-three people with MS who were taking part in a study on web-based physiotherapy (mean age 55.7±9.9 years, 63 female). They were included if they were over 18 years old, diagnosed with MS, EDSS 4.0-6.5, not currently exercising ≥ 30 minutes, twice per week. Participants were excluded if they had poor cognitive function (Mini Mental State Examination score < 24); had a relapse within the last three months; had a significant co-morbidity for which PA/exercise is contra-indicated. PA was measured using the activPAL3 activity monitor (PAL Technologies, Glasgow, Scotland), attached to the strongest or dominant leg using a waterproof dressing and worn continuously for one week.

Results: Overall participants accumulated 4,444±2,597 [67-13,920] steps/day, 54±15 [21-94] Sit-to-Stand (STS) transitions, were upright for 5.1±2.2 hours/day [standing = 4.0±1.9, stepping 1.1±0.6 hours/day] and sedentary for 18.9±2.2 hours/day. Due to the small number of participants with EDSS 4-5.5 statistical analysis was not possible however between EDSS levels 6.0 (n=46) and 6.5 (n=18) there were significant differences in steps taken (4,884±2,496 and 1,769±1,640 steps/day respectively; p≤0.001), upright time (5.5±2.3 and 3.5±1.9 hours/day; p=0.002), standing time (4.3±2.0 and 2.9±1.6 hours/day; p=0.014), walking time (1.2±0.6 and 0.6±0.5 hours/day; p≤0.001) and sedentary time (18.5±2.3 and 20.5±1.9 hours/day; p=0.002).

Conclusion: The significantly lower PA, and higher SB in those with EDSS 6.5 compared to 6.0 suggests that this is a transition point for people with MS. Sedentary time in those with EDSS 6.5 was similar to our previous work in stroke survivors (20.4 ± 2.7 h; Paul et al (2015). Further research is required to determine the effectiveness of rehabilitation strategies to improve/maintain PA and reduce SB in those with MS.

Disclosure: Coulter EH: Nothing to disclose

Freeman J:Nothing to disclose

Miller L: Nothing to disclose

Weller B: Nothing to disclose

McConnachie A:Nothing to disclose

Mattison PG: Nothing to disclose

Wu O:Nothing to disclose

Paul L: Nothing to disclose

Abstract: P1331

Type: Poster

Abstract Category: RIMS - Exercise

Introduction: Remaining physically active is important to maintain functional ability, independence, quality of life and reducing the incidence of co-morbid disease. People with Multiple Sclerosis (MS) may find it difficult to engage in Physical Activity (PA). Previous research in MS has focussed on PA in MS however sedentary behaviour (SB) is associated with increased cardiovascular risk in healthy and other clinical populations.

Objective: To assess the PA and SB profiles of people moderately affected by MS with respect to disability level.

Methods: Data is reported for eighty-three people with MS who were taking part in a study on web-based physiotherapy (mean age 55.7±9.9 years, 63 female). They were included if they were over 18 years old, diagnosed with MS, EDSS 4.0-6.5, not currently exercising ≥ 30 minutes, twice per week. Participants were excluded if they had poor cognitive function (Mini Mental State Examination score < 24); had a relapse within the last three months; had a significant co-morbidity for which PA/exercise is contra-indicated. PA was measured using the activPAL3 activity monitor (PAL Technologies, Glasgow, Scotland), attached to the strongest or dominant leg using a waterproof dressing and worn continuously for one week.

Results: Overall participants accumulated 4,444±2,597 [67-13,920] steps/day, 54±15 [21-94] Sit-to-Stand (STS) transitions, were upright for 5.1±2.2 hours/day [standing = 4.0±1.9, stepping 1.1±0.6 hours/day] and sedentary for 18.9±2.2 hours/day. Due to the small number of participants with EDSS 4-5.5 statistical analysis was not possible however between EDSS levels 6.0 (n=46) and 6.5 (n=18) there were significant differences in steps taken (4,884±2,496 and 1,769±1,640 steps/day respectively; p≤0.001), upright time (5.5±2.3 and 3.5±1.9 hours/day; p=0.002), standing time (4.3±2.0 and 2.9±1.6 hours/day; p=0.014), walking time (1.2±0.6 and 0.6±0.5 hours/day; p≤0.001) and sedentary time (18.5±2.3 and 20.5±1.9 hours/day; p=0.002).

Conclusion: The significantly lower PA, and higher SB in those with EDSS 6.5 compared to 6.0 suggests that this is a transition point for people with MS. Sedentary time in those with EDSS 6.5 was similar to our previous work in stroke survivors (20.4 ± 2.7 h; Paul et al (2015). Further research is required to determine the effectiveness of rehabilitation strategies to improve/maintain PA and reduce SB in those with MS.

Disclosure: Coulter EH: Nothing to disclose

Freeman J:Nothing to disclose

Miller L: Nothing to disclose

Weller B: Nothing to disclose

McConnachie A:Nothing to disclose

Mattison PG: Nothing to disclose

Wu O:Nothing to disclose

Paul L: Nothing to disclose

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