Contributions
Abstract: P1327
Type: Poster
Abstract Category: RIMS - Neuropsychology and fatigue management
Background: Cognitive impairment is a common symptom in MS and can have a substantial impact on quality of life. The evidence on the effectiveness of neuropsychological rehabilitation is still limited, but current data suggest that computer-assisted cognitive training can improve cognitive performance.
Objectives: Evaluate the effectiveness of a computer-aided cognitive training with autonomous work at home to improve cognitive performance in patients with MS.
Method: 62 patients with MS and mild cognitive impairment (41 women; age: 43 (sd: 9.34); disease duration and 10.51 (sd: 7.71) and EDSS 2.0 (median)) were randomized to intervention (n = 30) or no (Control n = 32) group. Neuropsychological assessment pre and post treatment with the Brief Battery of Neuropsychological Test (BRB-N). Multidomain Rehabilitation (memory, attention / processing speed and executive functions) was performed in 12 sessions (1 / week) for 1 hour and working paper / pencil at home.
Results: Controlling for age, schooling and baseline performance, the treatment group showed significant improvement in verbal memory variables (LTS: F = 10,418; p = 0.002), F = CLTR and SRT_LP: F= 20,514 and F = 17.002; p < 0.001), processing speed (SDMT: F = 4.886; p = 0.032), working memory (PASAT: F = 19.154, p < 0.001) and phonetic fluency (COWAT: F = 4.339; p = 0.042). The control group showed no improvement in any of the neuropsychological functions evaluated.
Discussion: The computer-assisted cognitive training and combined with reinforcement work at home is effective in promoting neuropsychological functions most commonly affected in MS patients.
Disclosure: Nothing to disclose
Abstract: P1327
Type: Poster
Abstract Category: RIMS - Neuropsychology and fatigue management
Background: Cognitive impairment is a common symptom in MS and can have a substantial impact on quality of life. The evidence on the effectiveness of neuropsychological rehabilitation is still limited, but current data suggest that computer-assisted cognitive training can improve cognitive performance.
Objectives: Evaluate the effectiveness of a computer-aided cognitive training with autonomous work at home to improve cognitive performance in patients with MS.
Method: 62 patients with MS and mild cognitive impairment (41 women; age: 43 (sd: 9.34); disease duration and 10.51 (sd: 7.71) and EDSS 2.0 (median)) were randomized to intervention (n = 30) or no (Control n = 32) group. Neuropsychological assessment pre and post treatment with the Brief Battery of Neuropsychological Test (BRB-N). Multidomain Rehabilitation (memory, attention / processing speed and executive functions) was performed in 12 sessions (1 / week) for 1 hour and working paper / pencil at home.
Results: Controlling for age, schooling and baseline performance, the treatment group showed significant improvement in verbal memory variables (LTS: F = 10,418; p = 0.002), F = CLTR and SRT_LP: F= 20,514 and F = 17.002; p < 0.001), processing speed (SDMT: F = 4.886; p = 0.032), working memory (PASAT: F = 19.154, p < 0.001) and phonetic fluency (COWAT: F = 4.339; p = 0.042). The control group showed no improvement in any of the neuropsychological functions evaluated.
Discussion: The computer-assisted cognitive training and combined with reinforcement work at home is effective in promoting neuropsychological functions most commonly affected in MS patients.
Disclosure: Nothing to disclose