Contributions
Abstract: P1116
Type: Poster
Abstract Category: Pathology and pathogenesis of MS - Neuropsychology
Background: and Objective: Frequently, multiple sclerosis (MS) patients complain of memory problems that may include difficulties to remember to perform certain actions at the right time in the future. This ability is known as prospective memory. One of the tests that has been used to assess this type of memory is the Rivermead Behavioural Memory Test (RBMT), nevertheless, it is not frequently used in the assessment of MS patients.
The aim of the present work is to study the RBMT as a tool to evaluate prospective memory in MS patients.
Method: We included MS patients with no history of alcohol or drug dependence, or medical or psychiatric disorder that could affect cognitive performance. Patients who had presented a relapse or who were treated with corticosteroid in the previous month, were not included. All patients underwent a neuropsychological assessment that included the RBMT and the Brief Repeatable Battery of Neuropsychological Tests (BRB-N). Patients also answered a depression questionnaire. All patients were assessed by the neurologist in order to obtain the Expanded Disability Status Scale (EDSS) score. The same procedure was repeated one and seven years later.
Results: A total of 96 patients (68 females) with a mean age of 36,9 years(SD=9,15), were included. Time of evolution of the disease was 6,7 years(SD=6,4) and median EDSS score was 2,0.
The Pearson correlation coefficient showed a positive and significant correlation(p< 0.05) between the RBMT and the subtests of the BRB-N in the three assessments, except for the 2 seconds version of the Paced Auditory Serial Addition Test where the correlation in the 2nd and 3rd assessments was not significant(p=0.078; 0.070).
A negative significant correlation was observed between the RBMT and the EDSS in the three evaluations.
The correlations between the RBMT and the depression questionnaire were not significant at the 2nd and 3rd evaluations.
In general, the higher correlations were observed between the RBMT and the visual and verbal memory tests and the symbol digit modalities test (SDMT) in all three evaluations (baseline, one and seven years).
Conclusions: In a follow-up period of 7 years, the results of the present study show a positive and significant correlation between the RBMT and the memory subtests of the BRB-N and with the SDMT that has shown to be a useful tool assess cognitive impairment in MS. These data support the use of the RBMT to assess prospective memory in MS.
Disclosure: Authors have nothing to disclose.
Abstract: P1116
Type: Poster
Abstract Category: Pathology and pathogenesis of MS - Neuropsychology
Background: and Objective: Frequently, multiple sclerosis (MS) patients complain of memory problems that may include difficulties to remember to perform certain actions at the right time in the future. This ability is known as prospective memory. One of the tests that has been used to assess this type of memory is the Rivermead Behavioural Memory Test (RBMT), nevertheless, it is not frequently used in the assessment of MS patients.
The aim of the present work is to study the RBMT as a tool to evaluate prospective memory in MS patients.
Method: We included MS patients with no history of alcohol or drug dependence, or medical or psychiatric disorder that could affect cognitive performance. Patients who had presented a relapse or who were treated with corticosteroid in the previous month, were not included. All patients underwent a neuropsychological assessment that included the RBMT and the Brief Repeatable Battery of Neuropsychological Tests (BRB-N). Patients also answered a depression questionnaire. All patients were assessed by the neurologist in order to obtain the Expanded Disability Status Scale (EDSS) score. The same procedure was repeated one and seven years later.
Results: A total of 96 patients (68 females) with a mean age of 36,9 years(SD=9,15), were included. Time of evolution of the disease was 6,7 years(SD=6,4) and median EDSS score was 2,0.
The Pearson correlation coefficient showed a positive and significant correlation(p< 0.05) between the RBMT and the subtests of the BRB-N in the three assessments, except for the 2 seconds version of the Paced Auditory Serial Addition Test where the correlation in the 2nd and 3rd assessments was not significant(p=0.078; 0.070).
A negative significant correlation was observed between the RBMT and the EDSS in the three evaluations.
The correlations between the RBMT and the depression questionnaire were not significant at the 2nd and 3rd evaluations.
In general, the higher correlations were observed between the RBMT and the visual and verbal memory tests and the symbol digit modalities test (SDMT) in all three evaluations (baseline, one and seven years).
Conclusions: In a follow-up period of 7 years, the results of the present study show a positive and significant correlation between the RBMT and the memory subtests of the BRB-N and with the SDMT that has shown to be a useful tool assess cognitive impairment in MS. These data support the use of the RBMT to assess prospective memory in MS.
Disclosure: Authors have nothing to disclose.