ECTRIMS eLearning

Perceived cognitive impairment in multiple sclerosis patients: assessment using a self-reported questionnaire
Author(s): ,
C Di Carmine
Affiliations:
University of L'Aquila
,
C Raparelli
Affiliations:
Neurology, University of L'Aquila, L'Aquila, Italy
,
S Sciamanna
Affiliations:
Neurology, University of L'Aquila, L'Aquila, Italy
,
P Cerrone
Affiliations:
Neurology, University of L'Aquila, L'Aquila, Italy
,
C Carrocci
Affiliations:
Neurology, University of L'Aquila, L'Aquila, Italy
,
C Marini
Affiliations:
Neurology, University of L'Aquila, L'Aquila, Italy
,
A Carolei
Affiliations:
Neurology, University of L'Aquila, L'Aquila, Italy
R Totaro
Affiliations:
Neurology, University of L'Aquila, L'Aquila, Italy
ECTRIMS Learn. di carmine c. 09/14/16; 145680; EP1585
caterina di carmine
caterina di carmine
Contributions
Abstract

Abstract: EP1585

Type: ePoster

Abstract Category: RIMS - Neuropsychology and fatigue management

Background and Objective: Discrepancy might exist between perception of cognitive functioning and cognitive performance in multiple sclerosis (MS) patients, as a consequence of under- or overestimation of cognitive dysfunction.

The aim of this study was to explore the correlation between perceived cognitive dysfunction on a self-reported questionnaire and performance on specific cognitive domains on Brief Repeatable Battery (BRB) in a cohort of patients with MS.

Methods: Sixty relapsing-remitting MS patients referred to our MS center were asked to complete the Perceived Cognitive Deficit (PCD) questionnaire, an 11 item self-reported assessment tool exploring the patient perceived degree of cognitive impairment in 6 major cognitive domains (verbal memory, visuo-spatial memory, learning, sustained attention and concentration, speed of information processing, and verbal fluency). Answers reported on a 5-degree scale were further converted into dummy variables (yes/no) according to low (grade 1-3) or high (grade 4-5) self-perception of cognitive impairment. Domain-specific perceived cognitive performance was then correlated with corresponding scores in selective BRB subtests exploring verbal memory (SRT-LTS, SRT-CLRT), visuo-spatial memory (SPART), learning (SRT-D SPART-D), sustained attention and concentration (SDMT), speed of information processing (PASAT-3, PASAT-2) and verbal fluency (WLG)

Results: Out of 60 included patients, 18 were men and 42 women. Mean age was 42.1±8.1 years. Mean duration of the disease was 10.4±5.8 years. Mean schooling value was 14.5±3.1 years: 22 patients perceived a deficit of verbal memory while a deficit was found in 27; 15 patients perceived a deficit of visuo-spatial learning while a deficit was found in 25; 16 patients perceived a deficit of learning while deficit was found in 29; 21 patients perceived a deficit of sustained attention and concentration while a deficit was found in 21; 15 patients perceived a deficit of speed of information processing while a deficit was found in 36, 18 patients perceived a deficit of verbal fluency while a deficit was found in 8.

Conclusions: Results of our study showed a discrepancy between perceived and estimated cognitive impairment in MS patients. For most of cognitive domains (verbal memory, visuo-spatial learning, learning, speed of information processing) patients underrated cognitive dysfunctions while the perception of deficit of verbal fluency was overestimated.

Disclosure: Di Carmine C nothing to disclose

Raparelli C nothing to disclose

Sciamanna S nothing to disclose

Cerrone P nothing to disclose

Carrocci C nothing to disclose

Marini C nothing to disclose

Carolei A nothing to disclose

Totaro R nothing to disclose

Abstract: EP1585

Type: ePoster

Abstract Category: RIMS - Neuropsychology and fatigue management

Background and Objective: Discrepancy might exist between perception of cognitive functioning and cognitive performance in multiple sclerosis (MS) patients, as a consequence of under- or overestimation of cognitive dysfunction.

The aim of this study was to explore the correlation between perceived cognitive dysfunction on a self-reported questionnaire and performance on specific cognitive domains on Brief Repeatable Battery (BRB) in a cohort of patients with MS.

Methods: Sixty relapsing-remitting MS patients referred to our MS center were asked to complete the Perceived Cognitive Deficit (PCD) questionnaire, an 11 item self-reported assessment tool exploring the patient perceived degree of cognitive impairment in 6 major cognitive domains (verbal memory, visuo-spatial memory, learning, sustained attention and concentration, speed of information processing, and verbal fluency). Answers reported on a 5-degree scale were further converted into dummy variables (yes/no) according to low (grade 1-3) or high (grade 4-5) self-perception of cognitive impairment. Domain-specific perceived cognitive performance was then correlated with corresponding scores in selective BRB subtests exploring verbal memory (SRT-LTS, SRT-CLRT), visuo-spatial memory (SPART), learning (SRT-D SPART-D), sustained attention and concentration (SDMT), speed of information processing (PASAT-3, PASAT-2) and verbal fluency (WLG)

Results: Out of 60 included patients, 18 were men and 42 women. Mean age was 42.1±8.1 years. Mean duration of the disease was 10.4±5.8 years. Mean schooling value was 14.5±3.1 years: 22 patients perceived a deficit of verbal memory while a deficit was found in 27; 15 patients perceived a deficit of visuo-spatial learning while a deficit was found in 25; 16 patients perceived a deficit of learning while deficit was found in 29; 21 patients perceived a deficit of sustained attention and concentration while a deficit was found in 21; 15 patients perceived a deficit of speed of information processing while a deficit was found in 36, 18 patients perceived a deficit of verbal fluency while a deficit was found in 8.

Conclusions: Results of our study showed a discrepancy between perceived and estimated cognitive impairment in MS patients. For most of cognitive domains (verbal memory, visuo-spatial learning, learning, speed of information processing) patients underrated cognitive dysfunctions while the perception of deficit of verbal fluency was overestimated.

Disclosure: Di Carmine C nothing to disclose

Raparelli C nothing to disclose

Sciamanna S nothing to disclose

Cerrone P nothing to disclose

Carrocci C nothing to disclose

Marini C nothing to disclose

Carolei A nothing to disclose

Totaro R nothing to disclose

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