Contributions
Abstract: EP1568
Type: ePoster
Abstract Category: Therapy - symptomatic - Quality of life
Purpose: In this study, we aimed to evaluate the frequency and severity of restless legs syndrome (RLS) in patients with Multiple Sclerosis (MS). In addition, the correlation of RLS-severity and clinical features and quality of life measures in this patient group was investigated.
Material and methods: This study included 100 patients with MS being followed up in outpatient clinics of Haseki Research and Training Hospital. Demographic features, duration of illness, onset-age, symptoms at onset, MS-type, number of attacks, oligoclonal band (OCB) positivity in cerebrospinal fluid (CSF), and current drugs were noted. Disability status was evaluated with expanded disability status scale (EDSS). The diagnosis of RLS was based on “Revised International Restless Legs Syndrome Study Group (IRLSSG) Questionnaire”. The severity of RLS was evaluated with “IRLLSG rating scale”. 36-item short form-health survey (SF-36) was administered to all of the patients. Severity of RLS and clinical features and health quality measures were correlated.
Results: The mean age of the patients was 35,1±8,8 (min:18; max: 55). Seventy out of 100 patients were females. The mean of ilness-duration, onset-age, attack-number and of EDSS was 7,3±4,7; 27,7±8,3; 4,2±2,2 and 2,6 ±1,2, respectively. Ninety percent of the patients were categorised as RRMS and 10% as SPMS. The frequency of RLS in the study population was 35%. OCB-positivity was 94,5%. The severity of RLS was high in 91,4 %. Gender and severity of RLS did not show any correlation (p=0.84). There was no statistically significant difference between MS patients with and without RLS in means of age, onset-age, gender, disability and MS-type (p>0.05). All domains of SF-36 revealed worse in MS patients with RLS. Severity of RLS had a statistically significant negative correlation with all domains of SF-36 except for the emotional role functioning.
Conclusion: Restless legs syndrome among MS patients was frequent with a moderate to high severity and had a negative effect on quality of life measures.
Disclosure:
Belgin Petek-Balci: nothing to disclose
Faruk Ozturk: nothing to disclose
Aytul Mutlu: nothing to disclose
Birgul Baştan: nothing to disclose
Ozlem Cokar: nothing to disclose
Abstract: EP1568
Type: ePoster
Abstract Category: Therapy - symptomatic - Quality of life
Purpose: In this study, we aimed to evaluate the frequency and severity of restless legs syndrome (RLS) in patients with Multiple Sclerosis (MS). In addition, the correlation of RLS-severity and clinical features and quality of life measures in this patient group was investigated.
Material and methods: This study included 100 patients with MS being followed up in outpatient clinics of Haseki Research and Training Hospital. Demographic features, duration of illness, onset-age, symptoms at onset, MS-type, number of attacks, oligoclonal band (OCB) positivity in cerebrospinal fluid (CSF), and current drugs were noted. Disability status was evaluated with expanded disability status scale (EDSS). The diagnosis of RLS was based on “Revised International Restless Legs Syndrome Study Group (IRLSSG) Questionnaire”. The severity of RLS was evaluated with “IRLLSG rating scale”. 36-item short form-health survey (SF-36) was administered to all of the patients. Severity of RLS and clinical features and health quality measures were correlated.
Results: The mean age of the patients was 35,1±8,8 (min:18; max: 55). Seventy out of 100 patients were females. The mean of ilness-duration, onset-age, attack-number and of EDSS was 7,3±4,7; 27,7±8,3; 4,2±2,2 and 2,6 ±1,2, respectively. Ninety percent of the patients were categorised as RRMS and 10% as SPMS. The frequency of RLS in the study population was 35%. OCB-positivity was 94,5%. The severity of RLS was high in 91,4 %. Gender and severity of RLS did not show any correlation (p=0.84). There was no statistically significant difference between MS patients with and without RLS in means of age, onset-age, gender, disability and MS-type (p>0.05). All domains of SF-36 revealed worse in MS patients with RLS. Severity of RLS had a statistically significant negative correlation with all domains of SF-36 except for the emotional role functioning.
Conclusion: Restless legs syndrome among MS patients was frequent with a moderate to high severity and had a negative effect on quality of life measures.
Disclosure:
Belgin Petek-Balci: nothing to disclose
Faruk Ozturk: nothing to disclose
Aytul Mutlu: nothing to disclose
Birgul Baştan: nothing to disclose
Ozlem Cokar: nothing to disclose