Contributions
Abstract: EP1468
Type: ePoster
Abstract Category: Pathology and pathogenesis of MS - Neuropsychology
Introduction: Multiple sclerosis (MS) patients have significantly higher lifetime rates of suicidal intent comparing with the general population. The aim of the present study was to assess the prevalence and the determinants for suicidal ideation (SI) in a large MS patient group.
Method: In this study were included 349 MS patients who consecutively attended our Regional MS Centre, during a two months period. All the patients completed a survey about their demographic characteristics, marital and occupational status, presence of children, education, disease and Disease Modifying Treatment (DMT) duration, MS course. Their disability level was evaluated using the Expanded Disability Status Scale (EDSS). SI was documented with questions from the Beck Depression Inventory-II.
Results: 18 (5.15%) patients had SI, of which 15 were women. The presence of SI was significantly associated with longer disease duration, higher number of relapses, lower levels of education, higher levels of physical disability and severe depression . 6 patients with SI had moderate depression and 9 had severe depression. From the EDSS functional scores, only the pyramidal and the cerebellar score presented a significant association with the SI. The type of DMT, MS course, marital and occupational status, and presence of children did not influence the prevalence of SI.
Conclusions: In our cohort, the risk profile for a possible suicidal MS patient will be: long duration of disease, unfavorable clinical course of MS, low level of education and severe depression.
Disclosure:
Acknowledgments: This study was supported by the internal research Grant of The University of Medicine and Pharmacy Targu Mures, Grant Number 18/2015
Abstract: EP1468
Type: ePoster
Abstract Category: Pathology and pathogenesis of MS - Neuropsychology
Introduction: Multiple sclerosis (MS) patients have significantly higher lifetime rates of suicidal intent comparing with the general population. The aim of the present study was to assess the prevalence and the determinants for suicidal ideation (SI) in a large MS patient group.
Method: In this study were included 349 MS patients who consecutively attended our Regional MS Centre, during a two months period. All the patients completed a survey about their demographic characteristics, marital and occupational status, presence of children, education, disease and Disease Modifying Treatment (DMT) duration, MS course. Their disability level was evaluated using the Expanded Disability Status Scale (EDSS). SI was documented with questions from the Beck Depression Inventory-II.
Results: 18 (5.15%) patients had SI, of which 15 were women. The presence of SI was significantly associated with longer disease duration, higher number of relapses, lower levels of education, higher levels of physical disability and severe depression . 6 patients with SI had moderate depression and 9 had severe depression. From the EDSS functional scores, only the pyramidal and the cerebellar score presented a significant association with the SI. The type of DMT, MS course, marital and occupational status, and presence of children did not influence the prevalence of SI.
Conclusions: In our cohort, the risk profile for a possible suicidal MS patient will be: long duration of disease, unfavorable clinical course of MS, low level of education and severe depression.
Disclosure:
Acknowledgments: This study was supported by the internal research Grant of The University of Medicine and Pharmacy Targu Mures, Grant Number 18/2015