Contributions
Abstract: EP1449
Type: ePoster
Abstract Category: Pathology and pathogenesis of MS - Imaging
Background: The ultrasound markers of progressive reduction in brain volume include the diameter of the third ventricle and the width of the frontal horns of the lateral ventricles. The aim of this study was to assess usefulness of transcranial sonography in evaluation of the width of the third ventricle and the width of the anterior horn of the lateral ventricle in patients with relapsing-remitting MS (RRMS) and secondary progressive MS (SPMS).
Method: 41 patients with RRMS and 23 with SPMS and 20 persons of the control group were included in the study. Using transcranial sonography at thalamus level, the diameter of the third ventricle, the width of the anterior horn of the lateral ventricle on the opposite side were evaluated. Comparisons were made between the group of patients with MS and the control group, between the group of patients with relapsing-remitting MS and the group of patients with secondary progressive MS. A potential link between the patients´ age, sex, EDSS score, relapse index (RRMS patients) and ultrasound parameters was assessed.
Results: A longer diameter of the third ventricle (6.64±2.4 vs 4.62±1.21 mm, p=0.0003) and wider frontal horns of the lateral ventricles (14.12±4.35 vs. 9.81±2.1 mm, p=0.0002) were found in patients with MS, as compared to the control group. A significantly longer diameter of the third ventricle were found in patients with SPMS (7.52±2.31 mm), as compared to the subjects with RRMS (6.14±2.3 mm)(p=0.03). There was a significant correlation between the diameter of the third ventricle and the age of patients
(r=0.27, p=0.03) and EDSS score (r=0.38, p=0.001).
Conclusion: The width of the third ventricle measured with transcranial sonography may be used in the indirect assessment of brain atrophy.
Disclosure: nothing to disclose
Abstract: EP1449
Type: ePoster
Abstract Category: Pathology and pathogenesis of MS - Imaging
Background: The ultrasound markers of progressive reduction in brain volume include the diameter of the third ventricle and the width of the frontal horns of the lateral ventricles. The aim of this study was to assess usefulness of transcranial sonography in evaluation of the width of the third ventricle and the width of the anterior horn of the lateral ventricle in patients with relapsing-remitting MS (RRMS) and secondary progressive MS (SPMS).
Method: 41 patients with RRMS and 23 with SPMS and 20 persons of the control group were included in the study. Using transcranial sonography at thalamus level, the diameter of the third ventricle, the width of the anterior horn of the lateral ventricle on the opposite side were evaluated. Comparisons were made between the group of patients with MS and the control group, between the group of patients with relapsing-remitting MS and the group of patients with secondary progressive MS. A potential link between the patients´ age, sex, EDSS score, relapse index (RRMS patients) and ultrasound parameters was assessed.
Results: A longer diameter of the third ventricle (6.64±2.4 vs 4.62±1.21 mm, p=0.0003) and wider frontal horns of the lateral ventricles (14.12±4.35 vs. 9.81±2.1 mm, p=0.0002) were found in patients with MS, as compared to the control group. A significantly longer diameter of the third ventricle were found in patients with SPMS (7.52±2.31 mm), as compared to the subjects with RRMS (6.14±2.3 mm)(p=0.03). There was a significant correlation between the diameter of the third ventricle and the age of patients
(r=0.27, p=0.03) and EDSS score (r=0.38, p=0.001).
Conclusion: The width of the third ventricle measured with transcranial sonography may be used in the indirect assessment of brain atrophy.
Disclosure: nothing to disclose