Abstract: EP1393
Type: ePoster
Abstract Category: Clinical aspects of MS - Clinical assessment tools
Background and goal: Evoked potentials have an important role in the diagnosis and follow up of Multiple Sclerosis and other demiyelinating disorders. The vestibular evoked myogenic potentials (VEMP) test is a non-invasive evoked potential test and has short-latency myogenic responses. VEMPs are short latency manifestations of vestibulo-ocular and vestibulocollic reflexes that are based on the utricle and saccule. The cervical VEMPs (cVEMPs) are mediated by the vestibular nuclei and uncrossed medial vestibulospinal tract descending in the lower brainstem and spinal cord. The goal of this study is to compare cVEMP responses between relapsing-remitting multiple sclerosis (RRMS) patients and normal hearing individuals.
Materials and methods: For the study group 25 patients with the diagnosis of RRMS and for the control group 30 subjects with normal hearing and without balance problems were included. In both groups, cVEMP test was performed. Pure tone audiometry, speech audiometry and immittance audiometry were also applied to RRMS and control groups.
Results: The mean age of patients were 34.7±5.7 years in the study group, 33.5±7.5 years in control group. In the study group 20 subjects (80%) were female and 5 subjects (20%) were male. In the control group 17 subjects (56.7%) were female and 13 subjects (43.3%) were male. There were statistically significant differences both in P1 wave latencies and P1-N1 latency differences between RRMS patients and control group (p< 0.05). No statistically significant difference in N1 wave latency was found between RRMS patients and control group (p> 0.05).
Conclusion: cVEMP P1 wave latencies were significantly prolonged in RRMS patients. cVEMPs are useful in evaluating central as well as peripheral otolithic function that are not easily diagnosed by conventional vestibular function tests, and may aid in investigating and localizing central lesions, particularly silent demiyelinating brainstem plaques.
Disclosure:
L Küfecioglu: nothing to disclose
B Müjdeci: nothing to disclose
I Sayın: nothing to disclose
S Cagirici: nothing to disclose
V Yayla: nothing to disclose
FT Kayhan: nothing to disclose
Abstract: EP1393
Type: ePoster
Abstract Category: Clinical aspects of MS - Clinical assessment tools
Background and goal: Evoked potentials have an important role in the diagnosis and follow up of Multiple Sclerosis and other demiyelinating disorders. The vestibular evoked myogenic potentials (VEMP) test is a non-invasive evoked potential test and has short-latency myogenic responses. VEMPs are short latency manifestations of vestibulo-ocular and vestibulocollic reflexes that are based on the utricle and saccule. The cervical VEMPs (cVEMPs) are mediated by the vestibular nuclei and uncrossed medial vestibulospinal tract descending in the lower brainstem and spinal cord. The goal of this study is to compare cVEMP responses between relapsing-remitting multiple sclerosis (RRMS) patients and normal hearing individuals.
Materials and methods: For the study group 25 patients with the diagnosis of RRMS and for the control group 30 subjects with normal hearing and without balance problems were included. In both groups, cVEMP test was performed. Pure tone audiometry, speech audiometry and immittance audiometry were also applied to RRMS and control groups.
Results: The mean age of patients were 34.7±5.7 years in the study group, 33.5±7.5 years in control group. In the study group 20 subjects (80%) were female and 5 subjects (20%) were male. In the control group 17 subjects (56.7%) were female and 13 subjects (43.3%) were male. There were statistically significant differences both in P1 wave latencies and P1-N1 latency differences between RRMS patients and control group (p< 0.05). No statistically significant difference in N1 wave latency was found between RRMS patients and control group (p> 0.05).
Conclusion: cVEMP P1 wave latencies were significantly prolonged in RRMS patients. cVEMPs are useful in evaluating central as well as peripheral otolithic function that are not easily diagnosed by conventional vestibular function tests, and may aid in investigating and localizing central lesions, particularly silent demiyelinating brainstem plaques.
Disclosure:
L Küfecioglu: nothing to disclose
B Müjdeci: nothing to disclose
I Sayın: nothing to disclose
S Cagirici: nothing to disclose
V Yayla: nothing to disclose
FT Kayhan: nothing to disclose