Contributions
Abstract: EP1388
Type: ePoster
Abstract Category: Clinical aspects of MS - Clinical assessment tools
The Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) was created as a brief, standardized and specific instrument for the evaluation of cognitive impairment (CI) in multiple sclerosis (MS). BICAMS has been easily performed in everyday clinical practice. However, there is still need more information about this tool compared to other neuropsychological batteries. The aim of the present study is to compare results of the BICAMS and Brief Repeatable Battery (BRB) in MS patients. The BRB and BICAMS were administered to relapsing remitting MS patients older than 18 years of age, and age, sex and education-matched healthy subjects. Patients were accepted cognitively impaired as they failure on at least two tests (scores below the fifth percentile) when compared to healthy controls (HC) on the BRB and as the failure on at least one test of the BICAMS. The agreement between the performances on the two batteries was assessed through Kappa statistic of Cohen. The Multiple Sclerosis Neuropsychological Screening Questionnaire (MSNQ), both a patient self-report (MSNQ-P) and an informant version (MSNQ-I) were also administered. A total of 168 MS patients (117 women) and 113 HC (84 women) were included in the study. Mean age was 36.4±9.8 years and 35.6±7.1, respectively. Mean scores of patients were lower compared to those of HC in all the cognitive measures examined. 51 patients (30.6%) on BRB, 46 patients (27.4%) on BICAMS, and 39 patients (23.2%) on both of the batteries were identified as impaired. 41 patients were identified as unimpaired on both of the batteries. Kappa agreement was 0.54 which corresponds to a moderate agreement. Mean MSNQ-I score was significantly lower in patients with CI on both BRB (p=0.004) and BICAMS (p=0.003) than patients without CI. There was no association between MSNQ-P and CI. In conclusion, this study confirms the feasibility of BICAMS for the identification of CI in everyday clinical practice in MS. Besides, informant version of MSNQ found significantly related to BICAMS.
Disclosure:
Serkan Ozakbas: nothing to disclose
Pinar Yigit: nothing to disclose
Hatice Limoncu: nothing to disclose
Turhan Kahraman: nothing to disclose
Abstract: EP1388
Type: ePoster
Abstract Category: Clinical aspects of MS - Clinical assessment tools
The Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) was created as a brief, standardized and specific instrument for the evaluation of cognitive impairment (CI) in multiple sclerosis (MS). BICAMS has been easily performed in everyday clinical practice. However, there is still need more information about this tool compared to other neuropsychological batteries. The aim of the present study is to compare results of the BICAMS and Brief Repeatable Battery (BRB) in MS patients. The BRB and BICAMS were administered to relapsing remitting MS patients older than 18 years of age, and age, sex and education-matched healthy subjects. Patients were accepted cognitively impaired as they failure on at least two tests (scores below the fifth percentile) when compared to healthy controls (HC) on the BRB and as the failure on at least one test of the BICAMS. The agreement between the performances on the two batteries was assessed through Kappa statistic of Cohen. The Multiple Sclerosis Neuropsychological Screening Questionnaire (MSNQ), both a patient self-report (MSNQ-P) and an informant version (MSNQ-I) were also administered. A total of 168 MS patients (117 women) and 113 HC (84 women) were included in the study. Mean age was 36.4±9.8 years and 35.6±7.1, respectively. Mean scores of patients were lower compared to those of HC in all the cognitive measures examined. 51 patients (30.6%) on BRB, 46 patients (27.4%) on BICAMS, and 39 patients (23.2%) on both of the batteries were identified as impaired. 41 patients were identified as unimpaired on both of the batteries. Kappa agreement was 0.54 which corresponds to a moderate agreement. Mean MSNQ-I score was significantly lower in patients with CI on both BRB (p=0.004) and BICAMS (p=0.003) than patients without CI. There was no association between MSNQ-P and CI. In conclusion, this study confirms the feasibility of BICAMS for the identification of CI in everyday clinical practice in MS. Besides, informant version of MSNQ found significantly related to BICAMS.
Disclosure:
Serkan Ozakbas: nothing to disclose
Pinar Yigit: nothing to disclose
Hatice Limoncu: nothing to disclose
Turhan Kahraman: nothing to disclose