Contributions
Abstract: EP1364
Type: ePoster
Abstract Category: Clinical aspects of MS - Epidemiology
Background: Schizophrenia has some similarities with Multiple Sclerosis (MS) regarding year of onset, sex ratio and range of prevalence.
Aim: The aim of this study is to estimate the risk of schizophrenia in the pre- and post-diagnostic period of an MS diagnosis compared to the background population.
Methods: The present study is designed as a nested case-cohort study based on Danish registers. A cohort of 5,084 MS patients was included and matched with a control population of 24,771 persons and linked to nation-wide registers. Logistic regression analyses were performed to estimate Odds Ratios (OR).
Result: In this study, we found 39 MS patients diagnosed with schizophrenia in the pre-diagnostic period and 24 MS patients in the post-diagnostic period of MS. The risk of schizophrenia before MS diagnosis shows an OR = 0.96 (95% CI = 0.66-1.40), and an OR = 0.62 (95% CI= 0.39-0.97) after diagnosis.
Conclusion: No increased risk of schizophrenia was found before or after the MS diagnosis in the MS cohort. MS patients have a lower risk of being diagnosed with schizophrenia compared to the background population.
Disclosure:
Huong Hoang: Nothing to disclose
Bjarne Laursen :Nothing to disclose
Elsebeth Nylev Stenager: Nothing to disclose
Egon Stenager: Nothing to disclose
Abstract: EP1364
Type: ePoster
Abstract Category: Clinical aspects of MS - Epidemiology
Background: Schizophrenia has some similarities with Multiple Sclerosis (MS) regarding year of onset, sex ratio and range of prevalence.
Aim: The aim of this study is to estimate the risk of schizophrenia in the pre- and post-diagnostic period of an MS diagnosis compared to the background population.
Methods: The present study is designed as a nested case-cohort study based on Danish registers. A cohort of 5,084 MS patients was included and matched with a control population of 24,771 persons and linked to nation-wide registers. Logistic regression analyses were performed to estimate Odds Ratios (OR).
Result: In this study, we found 39 MS patients diagnosed with schizophrenia in the pre-diagnostic period and 24 MS patients in the post-diagnostic period of MS. The risk of schizophrenia before MS diagnosis shows an OR = 0.96 (95% CI = 0.66-1.40), and an OR = 0.62 (95% CI= 0.39-0.97) after diagnosis.
Conclusion: No increased risk of schizophrenia was found before or after the MS diagnosis in the MS cohort. MS patients have a lower risk of being diagnosed with schizophrenia compared to the background population.
Disclosure:
Huong Hoang: Nothing to disclose
Bjarne Laursen :Nothing to disclose
Elsebeth Nylev Stenager: Nothing to disclose
Egon Stenager: Nothing to disclose