Contributions
Abstract: EP1360
Type: ePoster
Abstract Category: Clinical aspects of MS - Epidemiology
Background and objectives: Multiple sclerosis (MS) prevalence in Italy increased over the past years and varied between different regions. In 1996, in the L"Aquila district MS prevalence rate was 53.0/100.000. Continue accurate estimates of MS prevalence provide important insights into possible risk factors and socio-economic burden of disease.
The aim of this study was to estimate a reappraisal of MS prevalence rate in the L"Aquila district on December 31, 2014.
Methods: Complete case ascertainment was ensured by multiple overlapping sources: clinical records of the departments of neurology within the district and those from neighbouring, files of the neuroradiology services, records of the rehabilitation units, records of the National Health Service, and general practitioners. All patients diagnosed with MS according to Poser and then McDonald criteria, living in the L"Aquila district on the prevalence day, were included.
Results: The overall crude prevalence rate was 197.1/100.000 (95% CI 181.4-212.9), 274.9/100.000 (95% CI 249.0-300.8) in women and 114.4/100.000 (95% CI 92.2-131.6) in men. A total of 601 cases (432 women, 169 men, women/men ratio 2.5:1) were alive and resident in the study area by prevalence date. Mean age was 44.8±12.1 years, 45.0±12.2 in women and 44.8±12.3 in men.
Conclusions: Findings from our survey indicate that the L"Aquila district is a geographical area at very high risk for MS with a more 3-fold increase in prevalence rates over the last two decades.
Disclosure: RT received funding for travel or speaker honoraria from Almirall, Bayer, Biogen, Merck Serono, Novartis, Sanofi-Aventis, and TEVA.
Abstract: EP1360
Type: ePoster
Abstract Category: Clinical aspects of MS - Epidemiology
Background and objectives: Multiple sclerosis (MS) prevalence in Italy increased over the past years and varied between different regions. In 1996, in the L"Aquila district MS prevalence rate was 53.0/100.000. Continue accurate estimates of MS prevalence provide important insights into possible risk factors and socio-economic burden of disease.
The aim of this study was to estimate a reappraisal of MS prevalence rate in the L"Aquila district on December 31, 2014.
Methods: Complete case ascertainment was ensured by multiple overlapping sources: clinical records of the departments of neurology within the district and those from neighbouring, files of the neuroradiology services, records of the rehabilitation units, records of the National Health Service, and general practitioners. All patients diagnosed with MS according to Poser and then McDonald criteria, living in the L"Aquila district on the prevalence day, were included.
Results: The overall crude prevalence rate was 197.1/100.000 (95% CI 181.4-212.9), 274.9/100.000 (95% CI 249.0-300.8) in women and 114.4/100.000 (95% CI 92.2-131.6) in men. A total of 601 cases (432 women, 169 men, women/men ratio 2.5:1) were alive and resident in the study area by prevalence date. Mean age was 44.8±12.1 years, 45.0±12.2 in women and 44.8±12.3 in men.
Conclusions: Findings from our survey indicate that the L"Aquila district is a geographical area at very high risk for MS with a more 3-fold increase in prevalence rates over the last two decades.
Disclosure: RT received funding for travel or speaker honoraria from Almirall, Bayer, Biogen, Merck Serono, Novartis, Sanofi-Aventis, and TEVA.